(Q44483599)

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Hypoxia-induced cell death in human malignant glioma cells: energy deprivation promotes decoupling of mitochondrial cytochrome c release from caspase processing and necrotic cell death

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Europe PubMed Central

PubMed publication ID

3 December 2017

Hypoxia-induced cell death in human malignant glioma cells: energy deprivation promotes decoupling of mitochondrial cytochrome c release from caspase processing and necrotic cell death (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

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1 reference

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author name string

Steinbach JP

1

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Wolburg H

2

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Klumpp A

3

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Probst H

4

1 reference

Europe PubMed Central

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3 December 2017

Weller M

5

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Europe PubMed Central

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3 December 2017

publication date

1 July 2003

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Europe PubMed Central

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3 December 2017

Cell Death & Differentiation

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Europe PubMed Central

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3 December 2017

10

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Europe PubMed Central

PubMed publication ID

3 December 2017

7

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Europe PubMed Central

PubMed publication ID

3 December 2017

823-832

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Europe PubMed Central

PubMed publication ID

3 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401252

0 references

Direct measurement of pO2 distribution and bioreductive enzymes in human malignant brain tumors

1 reference

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Polarographic measurements of oxygen tension in human glioma and surrounding peritumoural brain tissue.

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Vascular apoptosis and involution in gliomas precede neovascularization: a novel concept for glioma growth and angiogenesis.

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Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF.

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Response of tumour cells to hypoxia: role of p53 and NFkB.

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Local endostatin treatment of gliomas administered by microencapsulated producer cells

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Antiangiogenic gene therapy in a rat glioma model using a dominant-negative vascular endothelial growth factor receptor 2.

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

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Hypoxia-induced apoptosis in human cells with normal p53 status and function, without any alteration in the nuclear protein level.

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Necrogenesis and Fas/APO-1 (CD95) expression in primary (de novo) and secondary glioblastomas

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Mechanisms of apoptosis in central nervous system tumors: application to theory

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Preferential expression of Fas/APO1 (CD95) and apoptotic cell death in perinecrotic cells of glioblastoma multiforme.

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Apoptosis and cell proliferation in human neuroepithelial tumors.

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Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

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Up-regulation of apoptosis inhibitory protein IAP-2 by hypoxia. Hif-1-independent mechanisms

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Hypoxia and drug resistance

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Prognostic value of tumour associated antigen immunoreactivity and apoptosis in cerebral glioblastomas: an analysis of 168 cases

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Biological evaluation of biopsies from adult cerebral astrocytomas: cell-growth/cell-suicide ratios and their relationship to patient survival.

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Regional metabolism of experimental brain tumors.

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Relationship between of blood flow, glucose metabolism, protein synthesis, glucose and ATP content in experimentally-induced glioma (RG1 2.2) of rat brain.

1 reference

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21 January 2018

Physiological properties of malignant tumours

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Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

1 reference

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Anti-Fas/APO-1 antibody-mediated apoptosis of cultured human glioma cells. Induction and modulation of sensitivity by cytokines

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21 January 2018

Death ligand/receptor-independent caspase activation mediates drug-induced cytotoxic cell death in human malignant glioma cells

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21 January 2018

Sensitization to CD95 ligand-induced apoptosis in human glioma cells by hyperthermia involves enhanced cytochrome c release.

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21 January 2018

Identification of p21 as a target of cycloheximide-mediated facilitation of CD95-mediated apoptosis in human malignant glioma cells

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21 January 2018

Hypoxic injury to developing glial cells: protective effect of high glucose.

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

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Expression and biological activity of X-linked inhibitor of apoptosis (XIAP) in human malignant glioma

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Predicting chemoresistance in human malignant glioma cells: the role of molecular genetic analyses.

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Four deaths and a funeral: from caspases to alternative mechanisms.

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Calpain and caspase: can you tell the difference?

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Calpain activation is upstream of caspases in radiation-induced apoptosis.

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Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2.

1 reference

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21 January 2018

Mitochondria and apoptosis

1 reference

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Two distinct pathways leading to nuclear apoptosis

1 reference

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21 January 2018

Cytochrome c: can't live with it--can't live without it.

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Immunochemotherapy of malignant glioma: synergistic activity of CD95 ligand and chemotherapeutics.

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Synchronous replication of SV 40 DNA in virus infected TC 7 cells induced by transient hypoxia

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Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation

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Hypoxia induces apoptosis in human neuroblastoma SK-N-MC cells by caspase activation accompanying cytochrome c release from mitochondria

1 reference

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Mechanisms of cell death in hypoxia/reoxygenation injury

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Tumor oxygenation: a new predictive parameter in locally advanced cancer of the uterine cervix

1 reference

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Energy status and radiobiological hypoxia at specified oxygen concentrations

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Role of hypoxia-induced Bax translocation and cytochrome c release in reoxygenation injury

1 reference

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7 January 2021

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Identifiers

10.1038/SJ.CDD.4401252

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

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