(Q44486148)

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Enhancement and selective production of phoslactomycin B, a protein phosphatase IIa inhibitor, through identification and engineering of the corresponding biosynthetic gene cluster

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scholarly article

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Europe PubMed Central

PubMed publication ID

3 December 2017

Enhancement and selective production of phoslactomycin B, a protein phosphatase IIa inhibitor, through identification and engineering of the corresponding biosynthetic gene cluster (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Kevin A Reynolds

5

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

author name string

Nadaraj Palaniappan

1

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Beom Seok Kim

2

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Yasuyo Sekiyama

3

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Hiroyuki Osada

4

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

language of work or name

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publication date

20 June 2003

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Europe PubMed Central

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3 December 2017

Journal of Biological Chemistry

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Europe PubMed Central

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3 December 2017

278

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

37

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

35552-35557

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Fostriecin: chemistry and biology

1 reference

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Phase I and pharmacokinetic study of the topoisomerase II catalytic inhibitor fostriecin.

1 reference

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Total synthesis of fostriecin (CI-920).

1 reference

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Protein phosphatase inhibitors calyculin A and fostriecin protect rabbit cardiomyocytes in late ischemia.

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Fostriecin, an inhibitor of protein phosphatase 2A, limits myocardial infarct size even when administered after onset of ischemia

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21 January 2018

Comparison of in vitro preconditioning responses of isolated pig and rabbit cardiomyocytes: effects of a protein phosphatase inhibitor, fostriecin.

1 reference

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21 January 2018

Protein phosphatase 2A enhances activation of human immunodeficiency virus type 1 by phorbol myristate acetate

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21 January 2018

Protein phosphatase 2A inhibitors, phoslactomycins. Effects on the cytoskeleton in NIH/3T3 cells

1 reference

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21 January 2018

PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

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21 January 2018

Cloning and characterization of the gene encoding 1-cyclohexenylcarbonyl coenzyme A reductase from Streptomyces collinus

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21 January 2018

FramePlot: a new implementation of the frame analysis for predicting protein-coding regions in bacterial DNA with a high G + C content.

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21 January 2018

Basic local alignment search tool

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21 January 2018

Identification of a cyclohexylcarbonyl CoA biosynthetic gene cluster and application in the production of doramectin

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21 January 2018

Biosynthesis of ansatrienin (mycotrienin) and naphthomycin. Identification and analysis of two separate biosynthetic gene clusters in Streptomyces collinus Tü 1892.

1 reference

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21 January 2018

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

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21 January 2018

A novel delta(3),delta(2)-enoyl-CoA isomerase involved in the biosynthesis of the cyclohexanecarboxylic acid-derived moiety of the polyketide ansatrienin A.

1 reference

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21 January 2018

Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases

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Expression, site-directed mutagenesis, and steady state kinetic analysis of the terminal thioesterase domain of the methymycin/picromycin polyketide synthase

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21 January 2018

A model of structure and catalysis for ketoreductase domains in modular polyketide synthases

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21 January 2018

Biochemical evidence for an editing role of thioesterase II in the biosynthesis of the polyketide pikromycin

1 reference

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21 January 2018

Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae

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21 January 2018

Forty years of genetics with Streptomyces: from in vivo through in vitro to in silico

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21 January 2018

Genetic manipulation of antibiotic-producing Streptomyces

1 reference

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21 January 2018

Cloning and characterization of the bleomycin biosynthetic gene cluster from Streptomyces verticillus ATCC15003.

1 reference

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21 January 2018

Gene disruption and replacement in the rapamycin-producing Streptomyces hygroscopicus strain ATCC 29253.

1 reference

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21 January 2018

Studies of new phosphate ester antifungal antibiotics phoslactomycins. II. Structure elucidation of phoslactomycins A to F.

1 reference

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21 January 2018

Novel microbial metabolites of the phoslactomycins family induce production of colony-stimulating factors by bone marrow stromal cells. I. Taxonomy, fermentation and biological properties.

1 reference

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21 January 2018

Novel microbial metabolites of the phoslactomycins family induce production of colony-stimulating factors by bone marrow stromal cells. II. Isolation, physico-chemical properties and structure determination

1 reference

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21 January 2018

Isolation and structure of phosphazomycin C

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21 January 2018

A new antifungal antibiotic, phosphazomycin A

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21 January 2018

Specific inhibitors of protein phosphatase 2A inhibit tumor metastasis through augmentation of natural killer cells

1 reference

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21 January 2018

Formal catalytic asymmetric total synthesis of fostriecin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305082200

21 January 2018

Formal total synthesis of fostriecin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305082200

21 January 2018

Asymmetric total synthesis of (+)-fostriecin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305082200

21 January 2018

Studies on new phosphate ester antifungal antibiotics phoslactomycins. I. Taxonomy, fermentation, purification and biological activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305082200

21 January 2018

Biosynthesis of ansatrienin. Nonincorporation of shikimic acid into the mC7N unit and stereochemistry of its conversion to the cyclohexanecarboxylic acid moiety

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M305082200

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

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