(Q44488090)

3 December 2017

title

Rapid tau aggregation and delayed hippocampal neuronal death induced by persistent thrombin signaling (English)

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3 December 2017

Zhiming Suo

1

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3 December 2017

Min Wu

2

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3 December 2017

Bruce A Citron

3

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3 December 2017

Robert E Palazzo

4

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3 December 2017

Barry W Festoff

5

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3 December 2017

language of work or name

English

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publication date

23 June 2003

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Journal of Biological Chemistry

3 December 2017

published in

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3 December 2017

volume

278

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3 December 2017

issue

39

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3 December 2017

page(s)

37681-37689

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Neurodegenerative tauopathies

3 December 2017

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

1 reference

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The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

The role of thrombin and thrombin receptors in ischemic, hemorrhagic and traumatic brain injury: deleterious or protective?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

Persistent protease-activated receptor 4 signaling mediates thrombin-induced microglial activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

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21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

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21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

Aberrant tau phosphorylation by glycogen synthase kinase-3beta and JNK3 induces oligomeric tau fibrils in COS-7 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

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21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

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21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

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21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

Thrombin, its receptor and protease nexin I, its potent serpin, in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

Thrombin interactions with central nervous system tissue and implications of these interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

Thrombin-induced reversal of astrocyte stellation is mediated by activation of protein kinase C beta-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

Thrombin-induced activation of cultured rodent microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

The cytoskeleton in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

Role of specific cell surface receptors in thrombin-stimulated cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

Acceleration of soft tissue repair by a thrombin-derived oligopeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

Mechanisms of neurofibrillary degeneration and the formation of neurofibrillary tangles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

The neurite retraction induced by lysophosphatidic acid increases Alzheimer's disease-like Tau phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

Thrombin causes neurite retraction in neuronal cells through activation of cell surface receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

Exogenous thrombin inhibits neuritogenesis in cultured neuroblastoma cells but not in rat hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

Modelling Alzheimer's disease in multiple transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301406200

21 January 2018

Identifiers

DOI

10.1074/JBC.M301406200

1 reference

3 December 2017

1 reference