(Q44495344)

3 December 2017

p130Cas Couples the tyrosine kinase Bmx/Etk with regulation of the actin cytoskeleton and cell migration (English)

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3 December 2017

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4

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3 December 2017

Yama A Abassi

1

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3 December 2017

Marko Rehn

series ordinal

2

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3 December 2017

Niklas Ekman

series ordinal

3

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3 December 2017

Kristiina Vuori

series ordinal

5

1 reference

3 December 2017

language of work or name

English

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publication date

28 June 2003

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Journal of Biological Chemistry

3 December 2017

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3 December 2017

278

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3 December 2017

35636-35643

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3 December 2017

37

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Cell migration: a physically integrated molecular process

3 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Molecular signaling mechanisms of cell migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Signaling through focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Biochemical signals and biological responses elicited by the focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Signaling through focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

FAK integrates growth-factor and integrin signals to promote cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Adhesion-linked kinases in cancer; emphasis on src, focal adhesion kinase and PI 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Interaction of two proline-rich sequences of cell adhesion kinase beta with SH3 domains of p130Cas-related proteins and a GTPase-activating protein, Graf

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Direct binding of the proline-rich region of protein tyrosine phosphatase 1B to the Src homology 3 domain of p130(Cas)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Src kinase plays an essential role in integrin-mediated tyrosine phosphorylation of Crk-associated substrate p130Cas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Characterization of the kinase activity essential for tyrosine phosphorylation of p130Cas in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Tyrosine phosphorylation of Crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of Crk-associated substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Src family kinases are required for integrin but not PDGFR signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Mechanisms of CAS substrate domain tyrosine phosphorylation by FAK and Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

SH2 domains recognize specific phosphopeptide sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Differential regulation of cell migration, actin stress fiber organization, and cell transformation by functional domains of Crk-associated substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Extracellular-regulated kinase activation and CAS/Crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

A tyrosine kinase profile of prostate carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

The Bmx tyrosine kinase is activated by IL-3 and G-CSF in a PI-3K dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Tyrosine 221 in Crk regulates adhesion-dependent membrane localization of Crk and Rac and activation of Rac signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Signaling network of the Btk family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Functions of the adapter protein Cas: signal convergence and the determination of cellular responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Integrin signalling: a new Cas(t) of characters enters the stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Rho GTPases: molecular switches that control the organization and dynamics of the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Crk family adaptors-signalling complex formation and biological roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

EPS8 and E3B1 transduce signals from Ras to Rac

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Etk/Bmx tyrosine kinase activates Pak1 and regulates tumorigenicity of breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Selective activation of small GTPase RhoA by tyrosine kinase Etk through its pleckstrin homology domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

Sensing the environment: a historical perspective on integrin signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

p130(Cas), an assembling molecule of actin filaments, promotes cell movement, cell migration, and cell spreading in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306438200

21 January 2018

Identifiers

DOI

10.1074/JBC.M306438200

1 reference

3 December 2017

1 reference