(Q44499464)

3 December 2017

title

Prostate-specific antigen-activated thapsigargin prodrug as targeted therapy for prostate cancer (English)

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Søren Brøgger Christensen

3 December 2017

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7

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3 December 2017

Samuel R Denmeade

1

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3 December 2017

Carsten M Jakobsen

2

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3 December 2017

Samuel Janssen

3

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3 December 2017

Saeed R Khan

4

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3 December 2017

Elizabeth S Garrett

5

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3 December 2017

Hans Lilja

6

1 reference

3 December 2017

John T Isaacs

8

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3 December 2017

language of work or name

English

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publication date

1 July 2003

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Journal of the National Cancer Institute

3 December 2017

published in

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3 December 2017

volume

95

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3 December 2017

issue

13

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3 December 2017

page(s)

990-1000

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Systematic review and meta-analysis of monotherapy compared with combined androgen blockade for patients with advanced prostate carcinoma

3 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.990

"Thymineless" death in androgen-independent prostatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.990

A supramicromolar elevation of intracellular free calcium ([Ca(2+)](i)) is consistently required to induce the execution phase of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.990

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.990

Kinetics of thapsigargin-Ca(2+)-ATPase (sarcoplasmic reticulum) interaction reveals a two-step binding mechanism and picomolar inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.990

Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.990

Thapsigargin induces a calmodulin/calcineurin-dependent apoptotic cascade responsible for the death of prostatic cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.990

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.990

The chymotrypsin-like activity of human prostate-specific antigen, gamma-seminoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.990

Concentration of enzymatically active prostate-specific antigen (PSA) in the extracellular fluid of primary human prostate cancers and human prostate cancer xenograft models

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.990

Design, synthesis, and pharmacological evaluation of thapsigargin analogues for targeting apoptosis to prostatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.990

Detection of localized caspase activity in early apoptotic cells by laser scanning cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F95.13.990

21 January 2018

Identifiers

DOI

10.1093/JNCI/95.13.990

1 reference

3 December 2017

1 reference