(Q44507288)

English

Proteasome inhibitors induce growth inhibition and apoptosis in myeloma cell lines and in human bone marrow myeloma cells irrespective of chromosome 13 deletion

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scholarly article

1 reference

Europe PubMed Central

3 December 2017

Proteasome inhibitors induce growth inhibition and apoptosis in myeloma cell lines and in human bone marrow myeloma cells irrespective of chromosome 13 deletion (English)

1 reference

Europe PubMed Central

3 December 2017

author name string

Ivana Zavrski

1

1 reference

Europe PubMed Central

3 December 2017

Cord Naujokat

2

1 reference

Europe PubMed Central

3 December 2017

Kathrin Niemöller

3

1 reference

Europe PubMed Central

3 December 2017

Christian Jakob

4

1 reference

Europe PubMed Central

3 December 2017

Ulrike Heider

5

1 reference

Europe PubMed Central

3 December 2017

Corinna Langelotz

6

1 reference

Europe PubMed Central

3 December 2017

Claudia Fleissner

7

1 reference

Europe PubMed Central

3 December 2017

Jan Eucker

8

1 reference

Europe PubMed Central

3 December 2017

Kurt Possinger

9

1 reference

Europe PubMed Central

3 December 2017

Orhan Sezer

10

1 reference

Europe PubMed Central

3 December 2017

publication date

8 July 2003

1 reference

Europe PubMed Central

3 December 2017

Journal of Cancer Research and Clinical Oncology

1 reference

Europe PubMed Central

3 December 2017

129

1 reference

Europe PubMed Central

3 December 2017

383-391

1 reference

Europe PubMed Central

3 December 2017

7

1 reference

Europe PubMed Central

3 December 2017

https://scigraph.springernature.com/pub.10.1007/s00432-003-0454-6

0 references

Unique role of cytogenetics in the prognosis of patients with myeloma receiving high-dose therapy and autotransplants

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High incidence of chromosome 13 deletion in multiple myeloma detected by multiprobe interphase FISH

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of 13q14 remains an independent adverse prognostic variable in multiple myeloma despite its frequent detection by interphase fluorescence in situ hybridization

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of angiogenic factors and tumor progression in human neuroblastoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteasome-dependent regulation of p21WAF1/CIP1 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p27Kip1 expression by contact inhibition as a prognostic index of human glioma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteasome inhibition: a new strategy in cancer treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detailed analysis of cell cycle kinetics upon proteasome inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular sequelae of proteasome inhibition in human multiple myeloma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the cell death program by inhibition of proteasome function

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hematotoxicity on human bone marrow- and umbilical cord blood-derived progenitor cells and in vitro therapeutic index of methoxymorpholinyldoxorubicin and its metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ATP assay is more sensitive than the succinate dehydrogenase inhibition test for predicting cell viability

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone marrow angiogenesis and its correlation with other disease characteristics in multiple myeloma in stage I versus stage II-III

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of G1 arrest and selective growth inhibition by lactacystin in human umbilical vein endothelial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of doxorubicin in combination with mafosfamide for in vitro elimination of myeloid and lymphoid tumor cells from human bone marrow

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanistic studies on the inactivation of the proteasome by lactacystin in cultured cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteasome inhibitors induce mitochondria-independent apoptosis in human glioma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo ubiquitination and proteasome-mediated degradation of p53(1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role and function of the 26S proteasome in proliferation and apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle progression and phenotypic modification of Ki67 antigen-negative G1- and G2-phase cells in phorbol ester-treated Molt-4 human leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of cell cycle subcompartments by flow cytometric estimation of DNA-RNA content in combination with dual-color immunofluorescence

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How proteolysis drives the cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteasome inhibitors: a novel class of potent and effective antitumor agents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical study on VEGF expression in endometrial carcinoma--comparison with p53 expression, angiogenesis, and tumor histologic grade

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of p21(Cip1/Waf1/Sdi1) and p27(Kip1) cyclin-dependent kinase inhibitors during human hematopoiesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biologic sequelae of nuclear factor-kappaB blockade in multiple myeloma: therapeutic applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteasome inhibitors induced caspase-dependent apoptosis and accumulation of p21WAF1/Cip1 in human immature leukemic cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lactacystin activates FLICE (caspase 8) protease and induces apoptosis in Fas-resistant adult T-cell leukemia cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the ubiquitin-proteasome pathway in apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proteasome controls the expression of a proliferation-associated nuclear antigen Ki-67

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Posttranslational modifications of the KI-67 protein coincide with two major checkpoints during mitosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappa B as a therapeutic target in multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanistic studies on the inactivation of the proteasome by lactacystin: a central role for clasto-lactacystin beta-lactone

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12851815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00432-003-0454-6

1 reference

Europe PubMed Central

3 December 2017

1 reference

Europe PubMed Central

3 December 2017

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