(Q44508437)

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Free radical trap phenyl-N-tert-butylnitrone protects against light damage but does not rescue P23H and S334ter rhodopsin transgenic rats from inherited retinal degeneration.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12853423%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Free radical trap phenyl-N-tert-butylnitrone protects against light damage but does not rescue P23H and S334ter rhodopsin transgenic rats from inherited retinal degeneration (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12853423%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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Isabelle Ranchon

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12853423%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Matthew M LaVail

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12853423%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Yashige Kotake

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12853423%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Robert E Anderson

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12853423%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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publication date

1 July 2003

1 reference

Europe PubMed Central

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5 November 2019

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12853423%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

23

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12853423%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

14

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12853423%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

6050-6057

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12853423%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Expression of cytokines and activation of transcription factors in lipopolysaccharide-administered rats and their inhibition by phenyl N-tert-butylnitrone (PBN)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional protection of photoreceptors from light-induced damage by dimethylthiourea and Ginkgo biloba extract

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basal protein phosphorylation is decreased and phosphatase activity increased by an antioxidant and a free radical trap in primary rat glia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of caspase-3 in the retina of transgenic rats with the rhodopsin mutation s334ter during photoreceptor degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential DNA binding activities of the transcription factors AP-1 and Oct-1 during light-induced apoptosis of photoreceptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial cell line-derived neurotrophic factor induces histologic and functional protection of rod photoreceptors in the rd/rd mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pigment epithelium-derived factor delays the death of photoreceptors in mouse models of inherited retinal degenerations

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of rhodopsin mis-sorting and constitutive activation in a transgenic rat model of retinitis pigmentosa.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A QTL on distal chromosome 3 that influences the severity of light-induced damage to mouse photoreceptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P23H rhodopsin transgenic rat: correlation of retinal function with histopathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic photoreceptor death in the rhodopsin knockout mouse in the presence and absence of c-fos

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Rpe65 Leu450Met variation increases retinal resistance against light-induced degeneration by slowing rhodopsin regeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extended photoreceptor viability by light stress in the RCS rats but not in the opsin P23H mutant rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinal uptake of intravitreally injected Hsc/Hsp70 and its effect on susceptibility to light damage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lens epithelium-derived growth factor promotes photoreceptor survival in light-damaged and RCS rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two animal models of retinal degeneration are rescued by recombinant adeno-associated virus-mediated production of FGF-5 and FGF-18.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic administration of phenyl-N-tert-butylnitrone protects the retina from light damage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of arrestin: requirement of phosphorylation as the negative charge on residues in synthetic peptides from the carboxyl-terminal region of rhodopsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo protection of photoreceptors from light damage by pigment epithelium-derived factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of photoreceptor apoptosis by activation of the glucocorticoid receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibroblast growth factor-2 decreases hyperoxia-induced photoreceptor cell death in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for two apoptotic pathways in light-induced retinal degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Susceptibility to retinal light damage in transgenic rats with rhodopsin mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basic fibroblast growth factor and local injury protect photoreceptors from light damage in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection by dimethylthiourea against retinal light damage in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparative study of methods of photoreceptor morphometry.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photoreceptor degeneration in inherited retinal dystrophy delayed by basic fibroblast growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection from cerebral ischemic injury in gerbils with the spin trap agent N-tert-butyl-alpha-phenylnitrone (PBN).

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endotoxin-induced mortality in rats is reduced by nitrones

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinitis pigmentosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of photoexcited rhodopsin in retinal rods: the roles of rhodopsin kinase and 48-kDa protein (arrestin)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenyl-T-butyl-nitrone is active against traumatic shock in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modification by oxygen free radical scavengers of the metabolic and cardiovascular effects of endotoxin infusion in conscious rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irreversible Effects of Visible Light on the Retina: Role of Vitamin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemistry of visual pigments. I. Purification and properties of bovine rhodopsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinal damage by light in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Action spectrum of retinal light-damage in albino rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spin trapping agent, phenyl N-tert-butyl nitrone, inhibits induction of nitric oxide synthase in endotoxin-induced shock in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linkage of photoreceptor degeneration by apoptosis with inherited defect in phototransduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis leads to photoreceptor degeneration in inherited retinal dystrophy of RCS rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular genetics of retinitis pigmentosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Light-induced acceleration of photoreceptor degeneration in transgenic mice expressing mutant rhodopsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo trapping of nitric oxide in the brain of neonatal rats treated with the HIV-1 envelope protein gp 120: protective effects of alpha-phenyl-tert-butylnitrone

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha 2-adrenergic agonists induce basic fibroblast growth factor expression in photoreceptors in vivo and ameliorate light damage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inherited retinal degeneration: exceptional genetic and clinical heterogeneity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polygenic disease and retinitis pigmentosa: albinism exacerbates photoreceptor degeneration induced by the expression of a mutant opsin in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of a mutant opsin gene increases the susceptibility of the retina to light damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spin trapping agent phenyl N-tert-butylnitrone protects against the onset of drug-induced insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection of mouse photoreceptors by survival factors in retinal degenerations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic cell death in retinal degenerations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinal degeneration in the rd mouse in the absence of c-fos

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The melatonin antagonist luzindole protects retinal photoreceptors from light damage in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of NF-kappaB, iNOS mRNA, COX2 mRNA, and COX catalytic activity by phenyl-N-tert-butylnitrone (PBN).

1 reference

https://pubmed.ncbi.nlm.nih.gov/12853423

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.23-14-06050.2003

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12853423%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12853423%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12853423%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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