(Q44524421)

English

Selective activation of the c-Jun N-terminal kinase (JNK) pathway fails to elicit Bax activation or apoptosis unless the phosphoinositide 3'-kinase (PI3K) pathway is inhibited

scientific article published in July 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Selective activation of the c-Jun N-terminal kinase (JNK) pathway fails to elicit Bax activation or apoptosis unless the phosphoinositide 3'-kinase (PI3K) pathway is inhibited (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

author name string

Sarah A Molton

1

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Daniel E Todd

2

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Simon J Cook

3

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

language of work or name

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publication date

1 July 2003

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

22

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

30

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

4690-4701

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1206692

0 references

Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase

1 reference

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Direct activation of mitochondrial apoptosis machinery by c-Jun N-terminal kinase in adult cardiac myocytes

1 reference

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

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7 January 2021

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Signal transduction by the JNK group of MAP kinases

1 reference

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

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Insulin-mediated cell proliferation and survival involve inhibition of c-Jun N-terminal kinases through a phosphatidylinositol 3-kinase- and mitogen-activated protein kinase phosphatase-1-dependent pathway

1 reference

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Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

1 reference

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Vinblastine-induced phosphorylation of Bcl-2 and Bcl-XL is mediated by JNK and occurs in parallel with inactivation of the Raf-1/MEK/ERK cascade

1 reference

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Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint

1 reference

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7 January 2021

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Inactivation of Bcl-2 by phosphorylation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-2 phosphorylation required for anti-apoptosis function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

The involvement of PI 3-K/Akt-dependent up-regulation of Mcl-1 in the prevention of apoptosis of Hep3B cells by interleukin-6.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The stress-activated protein kinase subfamily of c-Jun kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

CIKS, a connection to Ikappa B kinase and stress-activated protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

Akt negatively regulates the cJun N-terminal kinase pathway in PC12 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

Insulin-like growth factor-I inhibits the stress-activated protein kinase/c-Jun N-terminal kinase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of c-jun mediated by MAP kinases.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

p53 mediates bcl-2 phosphorylation and apoptosis via activation of the Cdc42/JNK1 pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

Nerve growth factor inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation, and cytochrome c release.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

MEKK1 binds directly to the c-Jun N-terminal kinases/stress-activated protein kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

7 January 2021

based on heuristic

inferred from DOI database lookup

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

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based on heuristic

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Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206692

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MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1206692

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

ResearchGate publication ID

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