(Q44525255)

3 December 2017

title

The tumour suppressor HACE1 controls cell migration by regulating Rac1 degradation (English)

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3 December 2017

S Castillo-Lluva

1

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3 December 2017

C-T Tan

2

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3 December 2017

M Daugaard

3

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3 December 2017

P H B Sorensen

4

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3 December 2017

A Malliri

5

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3 December 2017

language of work or name

English

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publication date

21 May 2012

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3 December 2017

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3 December 2017

volume

32

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3 December 2017

issue

13

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3 December 2017

page(s)

1735-1742

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Rho GTPases in cell biology

3 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

Proteasome-mediated degradation of Rac1-GTP during epithelial cell scattering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

Focal-adhesion targeting links caveolin-1 to a Rac1-degradation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

SUMOylation of the GTPase Rac1 is required for optimal cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

Ubiquitin-mediated proteasomal degradation of Rho proteins by the CNF1 toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

The E3 ubiquitin-ligase HACE1 catalyzes the ubiquitylation of active Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

Differential expression of a novel ankyrin containing E3 ubiquitin-protein ligase, Hace1, in sporadic Wilms' tumor versus normal kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

The Met tyrosine kinase receptor in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

Oligomerization-induced Modulation of TPR-MET Tyrosine Kinase Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

Integrins regulate Rac targeting by internalization of membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

Rac1-null mouse embryonic fibroblasts are motile and respond to platelet-derived growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

Analysis of activated GAPs and GEFs in cell lysates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.189

21 January 2018

Identifiers

DOI

10.1038/ONC.2012.189

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Dimensions Publication ID

3 December 2017

1053506374

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1 reference