(Q44536448)

English

Effects of NRA0045, a novel potent antagonist at dopamine D4, 5-HT2A, and alpha1 adrenaline receptors, and NRA0160, a selective D4 receptor antagonist, on phencyclidine-induced behavior and glutamate release in rats

scientific article published on 31 July 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Effects of NRA0045, a novel potent antagonist at dopamine D4, 5-HT2A, and alpha1 adrenaline receptors, and NRA0160, a selective D4 receptor antagonist, on phencyclidine-induced behavior and glutamate release in rats (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

author name string

T Abekawa

1

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

M Honda

2

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

K Ito

3

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

T Koyama

4

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

publication date

31 July 2003

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

number of pages

10

1 reference

based on heuristic

inferred from page(s)

Psychopharmacology

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

169

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

3-4

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

247-256

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

https://scigraph.springernature.com/pub.10.1007/s00213-003-1517-8

0 references

Dopamine and the Pathophysiology of Dyskinesias Induced by Antipsychotic Drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

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The 5-HT2A receptor antagonist M100907 is more effective in counteracting NMDA antagonist- than dopamine agonist-induced hyperactivity in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

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Modulation of MK-801-induced behaviour by noradrenergic agents in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

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Corticolimbic dopamine neurotransmission is temporally dissociated from the cognitive and locomotor effects of phencyclidine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

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Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

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Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

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5-Hydroxytryptamine2A serotonin receptors in the primate cerebral cortex: possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

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MS-377, a novel selective sigma(1) receptor ligand, reverses phencyclidine-induced release of dopamine and serotonin in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

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NMDA receptor function and human cognition: the effects of ketamine in healthy volunteers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of phencyclidine-induced hyperlocomotion by olanzapine, clozapine and serotonin receptor subtype selective antagonists in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral rating scales for assessing phencyclidine-induced locomotor activity, stereotypes behavior and ataxia in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topographical organization and relationship with ventral striatal compartments of prefrontal corticostriatal projections in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phencyclidine increases extracellular dopamine metabolites in rat medial frontal cortex as measured by in vivo dialysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The phencyclidine psychosis: phenomenology and treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT2A receptor or alpha1-adrenoceptor activation induces excitatory postsynaptic currents in layer V pyramidal cells of the medial prefrontal cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

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The dopamine hypothesis of schizophrenia and the antagonistic action of neuroleptic drugs--a review

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contrasting mechanisms of action and sensitivity to antipsychotics of phencyclidine versus amphetamine: importance of nucleus accumbens 5-HT2Asites for PCP-induced locomotion in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antipsychotic agents antagonize non-competitive N-methyl-D-aspartate antagonist-induced behaviors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phencyclidine-induced stereotyped behaviors in rats following specific neurotoxin lesions of the striatum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective 6OHDA-induced destruction of mesolimbic dopamine neurons: abolition of psychostimulant-induced locomotor activity in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phencyclidine: behavioral and biochemical evidence supporting a role for dopamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MK-801-induced hyperlocomotion: differential effects of M100907, SDZ PSD 958 and raclopride

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo characterization of the dopamine D4 receptor, serotonin 5-HT2A receptor and alpha-1 adrenoceptor antagonist (R)-(+)-2-amino-4-(4-fluorophenyl)-5-[1-[4-(4-fluorophenyl)-4-oxobutyl] pyrrolidin-3-yl]thiazole (NRA0045).

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increases in extracellular dopamine levels and locomotor activity after direct infusion of phencyclidine into the nucleus accumbens.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic PCP treatment elevates brain extracellular 5-HT: a microdialysis study in awake rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The atypical antipsychotic profile of NRA0045, a novel dopamine D4 and 5-hydroxytryptamine2A receptor antagonist, in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin induces excitatory postsynaptic potentials in apical dendrites of neocortical pyramidal cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clozapine blunts N-methyl-D-aspartate antagonist-induced psychosis: a study with ketamine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of lesions in the striatum, nucleus accumbens and medial raphe on phencyclidine-induced stereotyped behaviors and hyperactivity in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphetamine psychosis: behavioral and biochemical aspects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent advances in the phencyclidine model of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clozapine and haloperidol in moderately refractory schizophrenia: a 6-month randomized and double-blind comparison

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of clozapine, haloperidol, or M100907 on phencyclidine-activated glutamate efflux in the prefrontal cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A selective dopamine D4 receptor antagonist, NRA0160: a preclinical neuropharmacological profile

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional brain catecholamines and metabolites following THC, PCP and MK-801

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical evidence for glutamate as neurotransmitter in corticostriatal and corticothalamic fibres in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subanesthetic doses of ketamine stimulate psychosis in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prazosin inhibits MK-801-induced hyperlocomotion and dopamine release in the nucleus accumbens.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of phencyclidine-induced hyperlocomotion by clozapine and MDL 100,907 in rats reflects antagonism of 5-HT2A receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12898123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00213-003-1517-8

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

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