(Q44547298)

4 December 2017

title

Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion (English)

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4 December 2017

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Hua Wang

1

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4 December 2017

Winston S Chu

2

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4 December 2017

Tong Lu

3

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4 December 2017

Sandra J Hasstedt

4

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4 December 2017

Philip A Kern

5

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4 December 2017

Steven C Elbein

6

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4 December 2017

publication date

12 August 2003

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American Journal of Physiology - Endocrinology and Metabolism

4 December 2017

published in

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4 December 2017

volume

286

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4 December 2017

issue

1

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4 December 2017

page(s)

E1-7

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Sibling-based tests of linkage and association for quantitative traits

4 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00231.2003

Structure and organization of the human uncoupling protein 2 gene and identification of a common biallelic variant in Caucasian and African-American subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00231.2003

Uncoupling proteins and thermoregulation

21 January 2018

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Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose

21 January 2018

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Linkage Between Markers in the Vicinity of the Uncoupling Protein 2 Gene and Resting Metabolic Rate in Humans

21 January 2018

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Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans

21 January 2018

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Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action

21 January 2018

1 reference

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00231.2003

Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and Type II diabetes

21 January 2018

1 reference

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Evaluation of apolipoprotein A-II as a positional candidate gene for familial Type II diabetes, altered lipid concentrations, and insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00231.2003

Quantitative trait linkage analysis of lipid-related traits in familial type 2 diabetes: evidence for linkage of triglyceride levels to chromosome 19q.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00231.2003

Role of common sequence variants in insulin secretion in familial type 2 diabetic kindreds: the sulfonylurea receptor, glucokinase, and hepatocyte nuclear factor 1alpha genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00231.2003

A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00231.2003

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

21 January 2018

1 reference

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The mitochondrial uncoupling protein-2: current status

21 January 2018

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Recessive inheritance of obesity in familial non-insulin-dependent diabetes mellitus, and lack of linkage to nine candidate genes

21 January 2018

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Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

21 January 2018

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Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function.

21 January 2018

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Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance

21 January 2018

1 reference

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A functional polymorphism in the promoter of UCP2 enhances obesity risk but reduces type 2 diabetes risk in obese middle-aged humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00231.2003

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

21 January 2018

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Computer-simulation methods in human linkage analysis

21 January 2018

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The future of genetic studies of complex human diseases

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00231.2003

Uncoupling protein-2: evidence for its function as a metabolic regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00231.2003

A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00231.2003

Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00231.2003

Mutation screening and association of human retinoid X receptor gamma variation with lipid levels in familial type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00231.2003

The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00231.2003

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00231.2003

10.1152/AJPENDO.00231.2003

21 January 2018

Identifiers

DOI

1 reference

4 December 2017

1 reference