(Q44559388)

4 December 2017

title

Resistance of SHP-null mice to bile acid-induced liver damage (English)

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4 December 2017

Li Wang

1

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4 December 2017

Yunqing Han

2

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4 December 2017

Chang-Soo Kim

3

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4 December 2017

Yoon-Kwang Lee

4

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4 December 2017

David D Moore

5

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4 December 2017

language of work or name

English

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publication date

21 August 2003

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Journal of Biological Chemistry

4 December 2017

published in

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4 December 2017

volume

278

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4 December 2017

issue

45

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4 December 2017

page(s)

44475-44481

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Nuclear receptors and lipid physiology: opening the X-files

4 December 2017

cites work

1 reference

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Quantitative estimations of the contribution of different bile acid pathways to total bile acid synthesis in the rat.

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Two 7 alpha-hydroxylase enzymes in bile acid biosynthesis

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A novel nonhepatic hydroxycholesterol 7 alpha-hydroxylase that is markedly stimulated by interleukin-1 beta. Characterization in the immature rat ovary

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Expression of sterol 12alpha-hydroxylase alters bile acid pool composition in primary rat hepatocytes and in vivo

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Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

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Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

21 January 2018

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

21 January 2018

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The orphan nuclear receptor SHP utilizes conserved LXXLL-related motifs for interactions with ligand-activated estrogen receptors

21 January 2018

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The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression

21 January 2018

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Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner

21 January 2018

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Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

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Redundant pathways for negative feedback regulation of bile acid production

21 January 2018

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Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis

21 January 2018

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Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway

21 January 2018

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An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

21 January 2018

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The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

21 January 2018

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21 January 2018

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21 January 2018

Bile salt transporters

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The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade

21 January 2018

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Hepatic injury induced by bile salts: correlation between biochemical and morphological events

21 January 2018

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Differential modulation of cellular death and survival pathways by conjugated bile acids

21 January 2018

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Three distinct types of GnRH receptor characterized in the bullfrog.

21 January 2018

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Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4

21 January 2018

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The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp

21 January 2018

1 reference

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Effects of bile salt flux variations on the expression of hepatic bile salt transporters in vivo in mice

21 January 2018

1 reference

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Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia.

21 January 2018

1 reference

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Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

21 January 2018

1 reference

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The functional expression of sodium-dependent bile acid transport in Madin-Darby canine kidney cells transfected with the cDNA for microsomal epoxide hydrolase

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M305258200

1 reference

4 December 2017

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