(Q44559471)

English

Critical role for cathepsin B in mediating caspase-1-dependent interleukin-18 maturation and caspase-1-independent necrosis triggered by the microbial toxin nigericin

scientific article published in September 2003

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scholarly article

1 reference

Europe PubMed Central

4 December 2017

Critical role for cathepsin B in mediating caspase-1-dependent interleukin-18 maturation and caspase-1-independent necrosis triggered by the microbial toxin nigericin (English)

1 reference

Europe PubMed Central

4 December 2017

0 references

author name string

Hentze H

1

1 reference

Europe PubMed Central

4 December 2017

Lin XY

2

1 reference

Europe PubMed Central

4 December 2017

Choi MS

3

1 reference

Europe PubMed Central

4 December 2017

Porter AG

4

1 reference

Europe PubMed Central

4 December 2017

publication date

1 September 2003

1 reference

Europe PubMed Central

4 December 2017

Cell Death & Differentiation

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Europe PubMed Central

4 December 2017

10

1 reference

Europe PubMed Central

4 December 2017

956-968

1 reference

Europe PubMed Central

4 December 2017

9

1 reference

Europe PubMed Central

4 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401264

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Interleukin-18 regulates both Th1 and Th2 responses

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Interleukin 1 is processed and released during apoptosis

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Increased mature interleukin-1beta (IL-1beta) secretion from THP-1 cells induced by nigericin is a result of activation of p45 IL-1beta-converting enzyme processing.

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Involvement of caspase-1 and caspase-3 in the production and processing of mature human interleukin 18 in monocytic THP.1 cells

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Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme

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Identifiers

10.1038/SJ.CDD.4401264

1 reference

Europe PubMed Central

4 December 2017

1 reference

Europe PubMed Central

4 December 2017

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