(Q44573128)

4 December 2017

EGF receptor mediates adhesion-dependent activation of the Rac GTPase: a role for phosphatidylinositol 3-kinase and Vav2. (English)

1 reference

4 December 2017

Nathaly Marcoux

1

1 reference

PubMed ID

12955089

4 December 2017

Kristiina Vuori

series ordinal

2

1 reference

PubMed ID

12955089

4 December 2017

language of work or name

English

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publication date

1 September 2003

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4 December 2017

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4 December 2017

22

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4 December 2017

6100-6106

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4 December 2017

38

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206712

4 December 2017

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cites work

Integrin-mediated signals regulated by members of the rho family of GTPases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

Fibronectin, integrins, and growth control

21 January 2018

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The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

Vav2 is required for cell spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

Analysis of receptor signaling pathways by mass spectrometry: identification of vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

Stimulation of beta1 integrins on fibroblasts induces PDGF independent tyrosine phosphorylation of PDGF beta-receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

The protein-tyrosine phosphatase TCPTP regulates epidermal growth factor receptor-mediated and phosphatidylinositol 3-kinase-dependent signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

Tyrosine 221 in Crk regulates adhesion-dependent membrane localization of Crk and Rac and activation of Rac signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Requirement for Rho in integrin signalling.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Regulatory and signaling properties of the Vav family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Rho family proteins in cell adhesion and cell migration.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

A region of the 85-kilodalton (kDa) subunit of phosphatidylinositol 3-kinase binds the 110-kDa catalytic subunit in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Integrin-Specific Activation of Rac Controls Progression through the G1 Phase of the Cell Cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Vav family proteins couple to diverse cell surface receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Activation of Rac and Cdc42 by integrins mediates cell spreading

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

N terminus of Sos1 Ras exchange factor: critical roles for the Dbl and pleckstrin homology domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Mechanism of epidermal growth factor regulation of Vav2, a guanine nucleotide exchange factor for Rac

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Membrane-targeting is critical for the phosphorylation of Vav2 by activated EGF receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

The adaptor protein Shc couples a class of integrins to the control of cell cycle progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206712

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206712

1 reference

4 December 2017

1 reference

PubMed ID

12955089