(Q44586251)

4 December 2017

title

Pralnacasan, an inhibitor of interleukin-1beta converting enzyme, reduces joint damage in two murine models of osteoarthritis (English)

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4 December 2017

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K Rudolphi

1

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4 December 2017

N Gerwin

2

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4 December 2017

N Verzijl

3

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4 December 2017

P van der Kraan

4

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4 December 2017

W van den Berg

5

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4 December 2017

publication date

1 October 2003

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Osteoarthritis and Cartilage

4 December 2017

published in

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4 December 2017

volume

11

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4 December 2017

issue

10

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4 December 2017

page(s)

738-746

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Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States

4 December 2017

cites work

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7 January 2021

Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets

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7 January 2021

The role of cytokines and growth factors in cartilage destruction in osteoarthritis and rheumatoid arthritis

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https://api.crossref.org/works/10.1016%2FS1063-4584%2803%2900153-5

7 January 2021

Cytokines and their role in the pathophysiology of osteoarthritis

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https://api.crossref.org/works/10.1016%2FS1063-4584%2803%2900153-5

7 January 2021

Interleukin-1beta-converting enzyme/caspase-1 in human osteoarthritic tissues: localization and role in the maturation of interleukin-1beta and interleukin-18

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https://api.crossref.org/works/10.1016%2FS1063-4584%2803%2900153-5

7 January 2021

Relation between interleukin-18 and PGE2 in synovial fluid of osteoarthritis: a potential therapeutic target of cartilage degradation

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7 January 2021

Purification of interleukin-1 beta converting enzyme, the protease that cleaves the interleukin-1 beta precursor

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7 January 2021

Enhanced and coordinated in vivo expression of inflammatory cytokines and nitric oxide synthase by chondrocytes from patients with osteoarthritis

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7 January 2021

The interleukin-1 receptor in normal and osteoarthritic human articular chondrocytes. Identification as the type I receptor and analysis of binding kinetics and biologic function

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7 January 2021

Chondrocyte cytokine and growth factor expression in murine osteoarthritis.

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7 January 2021

A fibronectin fragment induces type II collagen degradation by collagenase through an interleukin-1-mediated pathway

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7 January 2021

Chondroprotective effect of intraarticular injections of interleukin-1 receptor antagonist in experimental osteoarthritis. Suppression of collagenase-1 expression

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7 January 2021

Effects of human recombinant interleukin-1beta on canine articular chondrocytes in three-dimensional culture.

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7 January 2021

Interleukin-1-induced interleukin-6 is required for the inhibition of proteoglycan synthesis by interleukin-1 in human articular cartilage

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7 January 2021

Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity

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7 January 2021

Morphologic characteristics of developing osteoarthrotic lesions in the knee cartilage of str/in mice

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7 January 2021

Collagen-induced arthritis in rhesus monkeys: evaluation of markers for inflammation and joint degradation.

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7 January 2021

Urinary excretion of pyridinium crosslinks: a new marker of bone resorption in metabolic bone disease

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7 January 2021

An analysis of 14 molecular markers for monitoring osteoarthritis: segregation of the markers into clusters and distinguishing osteoarthritis at baseline

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https://api.crossref.org/works/10.1016%2FS1063-4584%2803%2900153-5

7 January 2021

An analysis of 14 molecular markers for monitoring osteoarthritis. Relationship of the markers to clinical end-points

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7 January 2021

10.1016/S1063-4584(03)00153-5

Identifiers

DOI

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4 December 2017

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