(Q44595084)

4 December 2017

Chromosome engineering: prospects for gene therapy (English)

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4 December 2017

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Grimes BR

1

1 reference

PubMed ID

12032694

4 December 2017

Warburton PE

series ordinal

2

1 reference

PubMed ID

12032694

4 December 2017

Farr CJ

series ordinal

3

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4 December 2017

1 June 2002

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4 December 2017

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4 December 2017

9

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4 December 2017

713-718

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4 December 2017

11

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3301763

4 December 2017

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cites work

Functional reintroduction of human telomeres into mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Stringent sequence requirements for the formation of human telomeres

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Making sense of eukaryotic DNA replication origins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Centromeres: the missing link in the development of human artificial chromosomes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Formation of de novo centromeres and construction of first-generation human artificial microchromosomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Construction of YAC-based mammalian artificial chromosomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Mammalian artificial chromosome formation from circular alphoid input DNA does not require telomere repeats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Assay of centromere function using a human artificial chromosome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Human artificial chromosomes generated by modification of a yeast artificial chromosome containing both human alpha satellite and single-copy DNA sequences.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Genomic and genetic definition of a functional human centromere

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Gene targeting to the centromeric DNA of a human minichromosome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Use of a human minichromosome as a cloning and expression vector for mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Molecular and cytological analysis of a 5.5 Mb minichromosome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Functional expression and germline transmission of a human chromosome fragment in chimaeric mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Efficient male and female germline transmission of a human chromosomal vector in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

De novo chromosome formations by large-scale amplification of the centromeric region of mouse chromosomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Generation of transgenic mice and germline transmission of a mammalian artificial chromosome introduced into embryos by pronuclear microinjection.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Efficient in-vitro transfer of a 60-Mb mammalian artificial chromosome into murine and hamster cells using cationic lipids and dendrimers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

The centromere paradox: stable inheritance with rapidly evolving DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

De novo formation of several features of a centromere following introduction of a Y alphoid YAC into mammalian cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Hamster chromosomes containing amplified human alpha-satellite DNA show delayed sister chromatid separation in the absence of de novo kinetochore formation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Identification of centromeric antigens in dicentric Robertsonian translocations: CENP-C and CENP-E are necessary components of functional centromeres

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Molecular Cytogenetic Analysis of Eight Inversion Duplications of Human Chromosome 13q That Each Contain a Neocentromere

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Domain organization at the centromere and neocentromere

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Epigenetic analysis of kinetochore assembly on variant human centromeres

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Determining centromere identity: cyclical stories and forking paths.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

A solid foundation: functional specialization of centromeric chromatin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

The Assembly of Large BACs by in Vivo Recombination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Functional complementation of a genetic deficiency with human artificial chromosomes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Stable gene expression from a mammalian artificial chromosome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Generation of an approximately 2.4 Mb human X centromere-based minichromosome by targeted telomere-associated chromosome fragmentation in DT40.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Human mini-chromosomes with minimal centromeres

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Efficient modification of a human chromosome by telomere-directed truncation in high homologous recombination-proficient chicken DT40 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Human mini-chromosomes in mouse embryonal stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

The accuracy of segregation of human mini-chromosomes varies in different vertebrate cell lines, correlates with the extent of centromere formation and provides evidence for a trans-acting centromere maintenance activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

A structurally defined mini-chromosome vector for the mouse germ line.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Construction of neocentromere-based human minichromosomes by telomere-associated chromosomal truncation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Genomics and gene therapy. Artificial chromosomes coming to life

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Engineering human chromosomes for gene therapy studies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301763

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3301763

1 reference

4 December 2017

1 reference

PubMed ID

12032694