(Q44614146)

4 December 2017

title

Synthesis and X-ray crystal structures of substituted fluorobenzene and benzoquinone inhibitors of the tissue factor VIIa complex (English)

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4 December 2017

main subject

X-ray crystallography

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https://api.crossref.org/works/10.1016/J.BMCL.2003.08.002

20 March 2024

pharmaceutical science

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https://api.crossref.org/works/10.1016/J.BMCL.2003.08.002

20 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.002

20 March 2024

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https://api.crossref.org/works/10.1016/J.BMCL.2003.08.002

20 March 2024

author name string

John J. Parlow

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14552766

20 March 2024

Ravi G. Kurumbail

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14552766

20 March 2024

Roderick A. Stegeman

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14552766

20 March 2024

Anna M. Stevens

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14552766

20 March 2024

William C. Stallings

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14552766

20 March 2024

Michael S. South

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14552766

20 March 2024

language of work or name

English

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publication date

1 November 2003

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4 December 2017

3 November 2003

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14552766

full work available at URL

20 March 2024

https://api.elsevier.com/content/article/PII:S0960894X03008230?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.002

https://api.elsevier.com/content/article/PII:S0960894X03008230?httpAccept=text/plain

20 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.002

Bioorganic & Medicinal Chemistry Letters

20 March 2024

published in

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4 December 2017

volume

13

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4 December 2017

issue

21

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4 December 2017

page(s)

3721-3725

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Redefining medical treatment in the management of unstable angina

4 December 2017

cites work

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The inhibitors of the tissue factor:factor VII pathway

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Tissue factor pathway inhibitor: an update of potential implications in the treatment of cardiovascular disorders

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New advances in the discovery of thrombin and factor Xa inhibitors

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The role of tissue factor/factor VIIa in the pathophysiology of acute thrombotic formation

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Total synthesis and structural confirmation of the marine natural product Dysinosin A: a novel inhibitor of thrombin and Factor VIIa

20 March 2024

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Targeting thrombin and factor VIIa: design, synthesis, and inhibitory activity of functionally relevant indolizidinones

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Optimization of a screening lead for factor VIIa/TF.

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Inhibitors of the tissue factor/factor VIIa-induced coagulation: synthesis and in vitro evaluation of novel 2-aryl substituted pyrid

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Inhibitors of the tissue factor/factor VIIa-induced coagulation: synthesis and in vitro evaluation of novel specific 2-aryl substituted 4H-3,1-benzoxazin-4-ones

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Inhibitory activity of unsaturated fatty acids and anacardic acids toward soluble tissue factor-factor VIIa complex

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Effect of nafamostat mesilate, a synthetic protease inhibitor, on tissue factor-factor VIIa complex activity

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Synthetic substrates for human factor VIIa and factor VIIa-tissue factor

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Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex.

20 March 2024

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The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor

20 March 2024

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Structure of human factor VIIa and its implications for the triggering of blood coagulation

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Crystal structure of active site-inhibited human coagulation factor VIIa (des-Gla)

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Oxidations with potassium nitrosodisulfonate (Fremy's radical). Teuber reaction

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Identifiers

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4 December 2017

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