(Q44623962)

4 December 2017

title

Reovirus therapy stimulates endoplasmic reticular stress, NOXA induction, and augments bortezomib-mediated apoptosis in multiple myeloma (English)

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4 December 2017

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K R Kelly

1

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4 December 2017

C M Espitia

2

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4 December 2017

D Mahalingam

3

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4 December 2017

B O Oyajobi

4

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4 December 2017

M Coffey

5

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4 December 2017

F J Giles

6

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4 December 2017

J S Carew

7

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4 December 2017

S T Nawrocki

8

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4 December 2017

language of work or name

English

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publication date

17 October 2011

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4 December 2017

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4 December 2017

volume

31

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4 December 2017

issue

25

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4 December 2017

page(s)

3023-3038

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Proteolytic disassembly is a critical determinant for reovirus oncolysis

4 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Targeting endoplasmic reticulum protein transport: a novel strategy to kill malignant B cells and overcome fludarabine resistance in CLL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

JNK regulates the release of proapoptotic mitochondrial factors in reovirus-infected cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Reovirus therapy of tumors with activated Ras pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

A phase I trial of intratumoral administration of reovirus in patients with histologically confirmed recurrent malignant gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Proteasome inhibitor PS-341 induces apoptosis in cisplatin-resistant squamous cell carcinoma cells by induction of Noxa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Clinical trials with oncolytic reovirus: moving beyond phase I into combinations with standard therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Retinoic acid-inducible gene-I and interferon-beta promoter stimulator-1 augment proapoptotic responses following mammalian reovirus infection via interferon regulatory factor-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

RAD001 (everolimus) improves the efficacy of replicating adenoviruses that target colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Replication of a cytopathic strain of bovine viral diarrhea virus activates PERK and induces endoplasmic reticulum stress-mediated apoptosis of MDBK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Reovirus-based therapy for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Antiangiogenic cancer therapy combined with oncolytic virotherapy leads to regression of established tumors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Clinical course of patients with relapsed multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Effect of tumor microenvironment modulation on the efficacy of oncolytic virus therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Bevacizumab increases viral distribution in human anaplastic thyroid carcinoma xenografts and enhances the effects of E1A-defective adenovirus dl922-947.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Ras transformation mediates reovirus oncolysis by enhancing virus uncoating, particle infectivity, and apoptosis-dependent release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Extensive immunoglobulin production sensitizes myeloma cells for proteasome inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Myc regulates aggresome formation, the induction of Noxa, and apoptosis in response to the combination of bortezomib and SAHA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Aggresome disruption: a novel strategy to enhance bortezomib-induced apoptosis in pancreatic cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Proteasome inhibitor bortezomib modulates TLR4-induced dendritic cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Detection of myeloma in skeleton of mice by whole-body optical fluorescence imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Synergistic effects of oncolytic reovirus and cisplatin chemotherapy in murine malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

ER stress triggers apoptosis by activating BH3-only protein Bim

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Cyclophosphamide facilitates antitumor efficacy against subcutaneous tumors following intravenous delivery of reovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Targeting the tumor vasculature to improve the efficacy of oncolytic virus therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Bortezomib mediates antiangiogenesis in multiple myeloma via direct and indirect effects on endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Correlation between interferon sensitivity of reovirus isolates and ability to discriminate between normal and Ras-transformed cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Synergistic antitumor activity of oncolytic reovirus and chemotherapeutic agents in non-small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Oncogenic Ras promotes reovirus spread by suppressing IFN-beta production through negative regulation of RIG-I signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Immunosuppression promotes reovirus therapy of colorectal liver metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Pro-inflammatory cytokine/chemokine production by reovirus treated melanoma cells is PKR/NF-κB mediated and supports innate and adaptive anti-tumour immune priming

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Japanese encephalitis virus infection initiates endoplasmic reticulum stress and an unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Identification of interferon-beta-stimulated genes that inhibit angiogenesis in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Oncolytic viral therapy using reovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Reovirus oncolysis as a novel purging strategy for autologous stem cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Enhanced in vitro and in vivo cytotoxicity of combined reovirus and radiotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Transient infection of freshly isolated human colorectal tumor cells by reovirus T3D intermediate subviral particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

A phase I study of intravenous oncolytic reovirus type 3 Dearing in patients with advanced cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

Reovirus triggers cell type-specific proinflammatory responses dependent on the autocrine action of IFN-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.478

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.478

1 reference

Dimensions Publication ID

4 December 2017

1010906274

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1 reference