(Q44636378)

English

Synthesis and Ca2+-Mobilizing Activity of Purine-Modified Mimics of Adenophostin A: A Model for the Adenophostin−Ins(1,4,5)P3 Receptor Interaction

scientific article published on November 6, 2003

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scholarly article

1 reference

Europe PubMed Central

4 December 2017

Synthesis and Ca2+-mobilizing activity of purine-modified mimics of adenophostin A: a model for the adenophostin-Ins(1,4,5)P3 receptor interaction (English)

1 reference

Europe PubMed Central

4 December 2017

Synthesis and Ca2+-Mobilizing Activity of Purine-Modified Mimics of Adenophostin A: A Model for the Adenophostin−Ins(1,4,5)P3 Receptor Interaction (English)

1 reference

10.1021/JM030883F

https://api.crossref.org/works/10.1021/JM030883F

26 March 2024

molecular medicine

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10.1021/JM030883F

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26 March 2024

author name string

Heidi J. Rosenberg

1

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26 March 2024

Andrew M. Riley

2

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Europe PubMed Central

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26 March 2024

Alex J. Laude

3

0000-0002-3853-1187

1 reference

Europe PubMed Central

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26 March 2024

Colin W. Taylor

4

1 reference

Europe PubMed Central

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26 March 2024

Barry V. L. Potter

5

1 reference

Europe PubMed Central

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language of work or name

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publication date

1 November 2003

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4 December 2017

6 November 2003

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14584937

26 March 2024

full work available at URL

https://pubs.acs.org/doi/pdf/10.1021/jm030883f

1 reference

10.1021/JM030883F

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26 March 2024

Journal of Medicinal Chemistry

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Europe PubMed Central

4 December 2017

46

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4 December 2017

23

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Europe PubMed Central

4 December 2017

4860-4871

1 reference

Europe PubMed Central

4 December 2017

The versatility and universality of calcium signalling

1

1 reference

10.1021/JM030883F

https://api.crossref.org/works/10.1021/JM030883F

26 March 2024

IP3 receptors and their regulation by calmodulin and cytosolic Ca2+.

2

1 reference

10.1021/JM030883F

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26 March 2024

Angewandte Chemie

3

34

1972

author name string

Potter B. V. L.

publication date

1995

1 reference

10.1021/JM030883F

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26 March 2024

New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor

4

1 reference

10.1021/JM030883F

https://api.crossref.org/works/10.1021/JM030883F

26 March 2024

Interactions of inositol 1,4,5-trisphosphate (IP(3)) receptors with synthetic poly(ethylene glycol)-linked dimers of IP(3) suggest close spacing of the IP(3)-binding sites.

5

1 reference

10.1021/JM030883F

https://api.crossref.org/works/10.1021/JM030883F

26 March 2024

The Journal of Antibiotics

6

46

1647

author name string

Takahashi M.

publication date

1993

1 reference

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26 March 2024

Journal of Biological Chemistry

7

269

372

author name string

Takahashi M.

publication date

1994

1 reference

10.1021/JM030883F

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26 March 2024

Adenophostin-medicated quantal Ca2+ release in the purified and reconstituted inositol 1,4,5-trisphosphate receptor type 1

8

1 reference

10.1021/JM030883F

https://api.crossref.org/works/10.1021/JM030883F

26 March 2024

Structural analogues of D-myo-inositol-1,4,5-trisphosphate and adenophostin A: recognition by cerebellar and platelet inositol-1,4,5-trisphosphate receptors.

9

1 reference

10.1021/JM030883F

https://api.crossref.org/works/10.1021/JM030883F

26 March 2024

Disaccharide polyphosphates based upon adenophostin A activate hepatic D-myo-inositol 1,4,5-trisphosphate receptors.

10

1 reference

10.1021/JM030883F

https://api.crossref.org/works/10.1021/JM030883F

26 March 2024

Journal of the Chemical Society

15

1935

1947

author name string

Marwood R. D.

publication date

2000

1 reference

10.1021/JM030883F

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26 March 2024

Molecular Pharmacology

16

47

1211

author name string

Wilcox R. A.

publication date

1995

1 reference

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26 March 2024

Journal of Organic Chemistry

19

63

8824

author name string

Shuto S.

publication date

1998

1 reference

10.1021/JM030883F

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26 March 2024

Simplification of adenophostin A defines a minimal structure for potent glucopyranoside-based mimics of D-myo-inositol 1,4,5-trisphosphate

20

1 reference

10.1021/JM030883F

https://api.crossref.org/works/10.1021/JM030883F

26 March 2024

Spirophostins: conformationally restricted analogues of adenophostin A

22

1 reference

10.1021/JM030883F

https://api.crossref.org/works/10.1021/JM030883F

26 March 2024

Bicyclic analogues of D-myo-inositol 1,4,5-trisphosphate related to adenophostin A: synthesis and biological activity

23

1 reference

10.1021/JM030883F

https://api.crossref.org/works/10.1021/JM030883F

26 March 2024

European Journal of Organic Chemistry

25

3085

3092

author name string

de Kort M.

publication date

2000

1 reference

10.1021/JM030883F

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26 March 2024

Xylopyranoside-based agonists of D-myo-inositol 1,4,5-trisphosphate receptors: synthesis and effect of stereochemistry on biological activity

26

1 reference

10.1021/JM030883F

https://api.crossref.org/works/10.1021/JM030883F

26 March 2024

D-myo-inositol-1,4,5-trisphosphate and adenophostin mimics: importance of the spatial orientation of a phosphate group on the biological activity

27

1 reference

10.1021/JM030883F

https://api.crossref.org/works/10.1021/JM030883F

26 March 2024

Synthesis of glucopyranoside-based ligands for D-myo-inositol 1,4,5-trisphosphate receptors

28

1 reference

10.1021/JM030883F

https://api.crossref.org/works/10.1021/JM030883F

26 March 2024

Contribution of the adenine base to the activity of adenophostin A investigated using a base replacement strategy.

30

1 reference

10.1021/JM030883F

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26 March 2024

Total synthesis of nucleobase-modified adenophostin A mimics

31

1 reference

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26 March 2024

Synthesis of potent agonists of the D-myo-inositol 1,4, 5-trisphosphate receptor based on clustered disaccharide polyphosphate analogues of adenophostin A.

32

1 reference

10.1021/JM030883F

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26 March 2024

Structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with its ligand

34

1 reference

10.1021/JM030883F

https://api.crossref.org/works/10.1021/JM030883F

26 March 2024

Determinants of adenophostin A binding to inositol trisphosphate receptors

35

1 reference

10.1021/JM030883F

https://api.crossref.org/works/10.1021/JM030883F

26 March 2024

Association of the inositol (1,4,5)-trisphosphate receptor ligand binding site with phosphatidylinositol (4,5)-bisphosphate and adenophostin A

37

1 reference

10.1021/JM030883F

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Development and validation of a genetic algorithm for flexible docking

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Implications of protein flexibility for drug discovery

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1 reference

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Molecular recognition of adenophostin, a very potent Ca2+ inducer, at the D-myo-inositol 1,4,5-trisphosphate receptor.

40

1 reference

10.1021/JM030883F

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Planar stacking interactions of arginine and aromatic side-chains in proteins

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1 reference

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Structure-based analysis of protein-RNA interactions using the program ENTANGLE.

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1 reference

10.1021/JM030883F

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Crystal structure of the NADP+-dependent aldehyde dehydrogenase from Vibrio harveyi: structural implications for cofactor specificity and affinity

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1 reference

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Adenophostins A and B: Potent agonists of inositol-1,4,5-trisphosphate receptor produced by Penicillium brevicompactum. Taxonomy, fermentation, isolation, physico-chemical and biological properties.

1 reference

12 April 2024

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Identifiers

10.1021/JM030883F

1 reference

Europe PubMed Central

4 December 2017

1 reference

Europe PubMed Central

4 December 2017

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