(Q44649914)

English

Apoptotic cell death and altered calcium homeostasis caused by frataxin depletion in dorsal root ganglia neurons can be prevented by BH4 domain of Bcl-xL protein

scientific article published on 15 November 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Apoptotic cell death and altered calcium homeostasis caused by frataxin depletion in dorsal root ganglia neurons can be prevented by BH4 domain of Bcl-xL protein (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

apoptotic process

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24242291%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24242291%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Stefka Mincheva-Tasheva

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24242291%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Joaquim Ros

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24242291%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

publication date

15 November 2013

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Europe PubMed Central

PubMed publication ID

5 December 2017

Human Molecular Genetics

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24242291%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

23

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24242291%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24242291%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1829-1841

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24242291%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

1 reference

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DNA triplexes and Friedreich ataxia

1 reference

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Friedreich's ataxia: past, present and future

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GAA repeat expansion mutation mouse models of Friedreich ataxia exhibit oxidative stress leading to progressive neuronal and cardiac pathology

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Friedreich ataxia mouse models with progressive cerebellar and sensory ataxia reveal autophagic neurodegeneration in dorsal root ganglia

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Regulation of cell death: the calcium-apoptosis link

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Mitochondria, calcium-dependent neuronal death and neurodegenerative disease

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Distinct roles of mitochondria- and ER-localized Bcl-xL in apoptosis resistance and Ca2+ homeostasis

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Fusion of the tetanus toxin C fragment binding domain and Bcl-xL for protection of peripheral nerve neurons.

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21 January 2018

Bax and Bcl-xL independently regulate apoptotic changes of yeast mitochondria that require VDAC but not adenine nucleotide translocator

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BCL-XL regulates TNF-alpha-mediated cell death independently of NF-kappaB, FLIP and IAPs

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The canonical nuclear factor-κB pathway regulates cell survival in a developmental model of spinal cord motoneurons.

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Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress

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21 January 2018

Frataxin is reduced in Friedreich ataxia patients and is associated with mitochondrial membranes

1 reference

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21 January 2018

Regulation of aberrant neurofilament phosphorylation in neuronal perikarya. III. Alterations following single and continuous /gB,ß′-iminodipropionitrile administrations

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21 January 2018

Silencing of frataxin gene expression triggers p53-dependent apoptosis in human neuron-like cells

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21 January 2018

Frataxin deficiency enhances apoptosis in cells differentiating into neuroectoderm

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21 January 2018

Calcium dysregulation and homeostasis of neural calcium in the molecular mechanisms of neurodegenerative diseases provide multiple targets for neuroprotection

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21 January 2018

Protective action of neuronal nitric oxide synthase inhibitor in the MPTP mouse model of Parkinson's disease

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21 January 2018

Differential expression of apoptotic proteins following hypoxia-induced CREB phosphorylation in the cerebral cortex of newborn piglets.

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21 January 2018

BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death

1 reference

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21 January 2018

Frataxin depletion in yeast triggers up-regulation of iron transport systems before affecting iron-sulfur enzyme activities

1 reference

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21 January 2018

Multicellular models of Friedreich ataxia.

1 reference

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21 January 2018

Frataxin deficiency leads to defects in expression of antioxidants and Nrf2 expression in dorsal root ganglia of the Friedreich's ataxia YG8R mouse model

1 reference

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21 January 2018

Neurofilament proteins in neurodegenerative diseases

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21 January 2018

Friedreich's ataxia: oxidative stress and cytoskeletal abnormalities.

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21 January 2018

Regulation of neurofilament dynamics by phosphorylation

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21 January 2018

Accumulation of cortical hyperphosphorylated neurofilaments as a marker of neurodegeneration in multiple sclerosis

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21 January 2018

Mitochondria as a central sensor for axonal degenerative stimuli.

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Calpastatin reduces calpain and caspase activation in methamphetamine-induced toxicity in human neuroblastoma SH-SY5Y cultured cells

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Nitric oxide synthase inhibitors enhance mechanosensitive Ca(2+) influx in cultured dorsal root ganglion neurons

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Upregulation of neuronal nitric oxide synthase in the periphery promotes pain hypersensitivity after peripheral nerve injury

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The roles of nitric oxide in dorsal root ganglion neurons

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The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis

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Protein transduction technology

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Detrimental effects of antiapoptotic treatments in spinal cord injury.

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Tat-Frataxin protects dopaminergic neuronal cells against MPTP-induced toxicity in a mouse model of Parkinson's disease

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A TAT-frataxin fusion protein increases lifespan and cardiac function in a conditional Friedreich's ataxia mouse model

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The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor

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The BH4 domain of Bcl-XL rescues astrocyte degeneration in amyotrophic lateral sclerosis by modulating intracellular calcium signals

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[35] Assessment of peroxynitrite scavengers in Vitro

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