(Q44658338)

5 December 2017

title

Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept) to cholinesterases (English)

1 reference

5 December 2017

Aromatic amino‐acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept®) to cholinesterases (English)

1 reference

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03837.X

2 April 2024

1 reference

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03837.X

2 April 2024

author name string

Ashima Saxena

1

1 reference

5 December 2017

Rohit Medhekar

4

1 reference

5 December 2017

Zoran Radić

5

1 reference

5 December 2017

Palmer Taylor

6

1 reference

5 December 2017

Oksana Lockridge

7

1 reference

5 December 2017

James M. Fedorko

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14622273

2 April 2024

C. R. Vinayaka

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14622273

2 April 2024

Bhupendra P. Doctor

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14622273

2 April 2024

language of work or name

English

0 references

publication date

1 November 2003

1 reference

full work available at URL

5 December 2017

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1046/j.1432-1033.2003.03837.x

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14622273

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1046%2Fj.1432-1033.2003.03837.x

2 April 2024

1 reference

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03837.X

https://febs.onlinelibrary.wiley.com/doi/pdf/10.1046/j.1432-1033.2003.03837.x

2 April 2024

1 reference

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03837.X

2 April 2024

1 reference

5 December 2017

volume

270

1 reference

5 December 2017

issue

22

1 reference

5 December 2017

page(s)

4447-4458

1 reference

Neurotransmitter-related enzymes in senile dementia of the alzheimer type

5 December 2017

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Acetylcholine and choline levels in post-mortem human brain tissue: preliminary observations in Alzheimer's disease.

21 January 2018

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Essential role of neocortical acetylcholine in spatial memory

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Physostigmine effects in Alzheimer's disease: relationship to dementia severity.

21 January 2018

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The rationale for E2020 as a potent acetylcholinesterase inhibitor.

21 January 2018

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Kinetic study on the inhibition of acetylcholinesterase by 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride (E2020).

21 January 2018

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The simulated binding of (+/-)-2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]meth yl] -1H-inden-1-one hydrochloride (E2020) and related inhibitors to free and acylated acetylcholinesterases and corresponding structure-activity analyse

21 January 2018

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Donepezil improves cognition and global function in Alzheimer disease: a 15-week, double-blind, placebo-controlled study. Donepezil Study Group.

21 January 2018

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Structure of acetylcholinesterase complexed with E2020 (Aricept): implications for the design of new anti-Alzheimer drugs

21 January 2018

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A simplified procedure for the purification of large quantities of fetal bovine serum acetylcholinesterase

21 January 2018

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Aspartate 74 as a primary determinant in acetylcholinesterase governing specificity to cationic organophosphonates

21 January 2018

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A new and rapid colorimetric determination of acetylcholinesterase activity

21 January 2018

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Direct determination of E2020 enantiomers in plasma by liquid chromatography-mass spectrometry and column-switching techniques

21 January 2018

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Organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase: synergy results in a somanase

21 January 2018

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Differences in active site gorge dimensions of cholinesterases revealed by binding of inhibitors to human butyrylcholinesterase

21 January 2018

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The cholinergic hypothesis--ten years on.

21 January 2018

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Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type.

2 April 2024

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Donepezil use in Alzheimer disease

2 April 2024

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Novel piperidine derivatives. Synthesis and anti-acetylcholinesterase activity of 1-benzyl-4-[2-(N-benzoylamino)ethyl]piperidine derivatives.

2 April 2024

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Novel benzisoxazole derivatives as potent and selective inhibitors of acetylcholinesterase.

2 April 2024

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Synthesis and structure-activity relationships of acetylcholinesterase inhibitors: 1-benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine hydrochloride and related compounds

2 April 2024

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Muscarinic receptor subtypes

2 April 2024

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The efficacy and safety of donepezil in patients with Alzheimer's disease: results of a US Multicentre, Randomized, Double-Blind, Placebo-Controlled Trial. The Donepezil Study Group.

2 April 2024

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Quantitative structure-activity relationship. QSAR, analyses of the substituted indanone and benzylpiperidine rings of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase

2 April 2024

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Conformational analyses and molecular-shape comparisons of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase

2 April 2024

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Prediction of the binding site of 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine in acetylcholinesterase by docking studies with the SYSDOC program

2 April 2024

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1 reference

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Three distinct domains in the cholinesterase molecule confer selectivity for acetyl- and butyrylcholinesterase inhibitors

2 April 2024

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Molecular recognition in acetylcholinesterase catalysis: free-energy correlations for substrate turnover and inhibition by trifluoro ketone transition-state analogs

2 April 2024

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Acetylcholinesterase inhibition by fasciculin: crystal structure of the complex

2 April 2024

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Conversion of acetylcholinesterase to butyrylcholinesterase: modeling and mutagenesis

2 April 2024

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1 reference

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03837.X

Asp7O in the peripheral anionic site of human butyrylcholinesterase

2 April 2024

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1 reference

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03837.X

Identification of amino acid residues involved in the binding of Huperzine A to cholinesterases

2 April 2024

35

1 reference

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Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A

2 April 2024

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1 reference

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Amino acid residues controlling acetylcholinesterase and butyrylcholinesterase specificity

2 April 2024

37

1 reference

https://api.crossref.org/works/10.1046/J.1432-1033.2003.03837.X

2 April 2024

Identifiers

1 reference

5 December 2017

1 reference