(Q44660894)

English

Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARgamma2 in the modulation of insulin secretion.

scientific article published on 18 November 2003

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scholarly article

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Europe PubMed Central

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21 December 2019

Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARgamma2 in the modulation of insulin secretion (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14625208%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

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1 reference

based on heuristic

inferred from title

(RS)-rosiglitazone

1 reference

based on heuristic

inferred from title

Piero Marchetti

7

1 reference

Europe PubMed Central

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21 December 2019

Stefano Del Prato

8

1 reference

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21 December 2019

Lorella Marselli

3

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21 December 2019

4

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21 December 2019

author name string

R Lupi

1

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21 December 2019

S Del Guerra

2

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21 December 2019

U Boggi

5

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21 December 2019

F Mosca

6

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21 December 2019

publication date

18 November 2003

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21 December 2019

American Journal of Physiology - Endocrinology and Metabolism

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21 December 2019

286

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21 December 2019

4

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21 December 2019

E560-7

1 reference

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21 December 2019

Insulin production by human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

PPARgamma, the ultimate thrifty gene

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Enhancing effects of long-term elevated glucose and palmitate on stored and secreted proinsulin-to-insulin ratios in human pancreatic islets

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Intracellular depletion of insulin: a comparative study with palmitate, oleate and elaidate in INS-1 cells.

1 reference

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21 January 2018

Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Response of pancreatic beta-cells to improved insulin sensitivity in women at high risk for type 2 diabetes

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes

1 reference

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21 January 2018

Treatment with the oral antidiabetic agent troglitazone improves beta cell responses to glucose in subjects with impaired glucose tolerance

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation.

1 reference

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21 January 2018

Peroxisome proliferator-activated receptors: nuclear control of metabolism

1 reference

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21 January 2018

Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2

1 reference

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21 January 2018

Beta-cell mass dynamics in Zucker diabetic fatty rats. Rosiglitazone prevents the rise in net cell death

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Acute effects of fatty acids on insulin secretion from rat and human islets of Langerhans

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men.

1 reference

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21 January 2018

Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships

1 reference

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21 January 2018

PPAR Tissue Distribution and Interactions with Other Hormone-Signaling Pathways

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Lipotoxicity in human pancreatic islets and the protective effect of metformin

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

The biguanide compound metformin prevents desensitization of human pancreatic islets induced by high glucose

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Lowering fatty acids potentiates acute insulin response in first degree relatives of people with type II diabetes.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Are the beta-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM?

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Lipoapoptosis in beta-cells of obese prediabetic fa/fa rats. Role of serine palmitoyltransferase overexpression

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Lipotoxicity and glucotoxicity in type 2 diabetes. Effects on development and progression.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Rosiglitazone (BRL 49653) enhances insulin secretory response via phosphatidylinositol 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Suppression of beta cell energy metabolism and insulin release by PGC-1alpha

1 reference

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21 January 2018

A fatty acid-induced decrease in pyruvate dehydrogenase activity is an important determinant of beta-cell dysfunction in the obese diabetic db/db mouse.

1 reference

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21 January 2018

Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2002

21 January 2018

Role of peroxisome proliferator-activated receptor alpha in disease of pancreatic beta cells

1 reference

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21 January 2018

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