(Q44669068)

English

Suppression of macrophage eicosanoid synthesis by atherogenic lipoproteins is profoundly affected by cholesterol-fatty acyl esterification and the Niemann-Pick C pathway of lipid trafficking

scientific article published on 24 November 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Suppression of macrophage eicosanoid synthesis by atherogenic lipoproteins is profoundly affected by cholesterol-fatty acyl esterification and the Niemann-Pick C pathway of lipid trafficking (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

atherosclerosis

1 reference

based on heuristic

inferred from title

Niemann–Pick disease, type C

1 reference

based on heuristic

inferred from title

author name string

Andrew R Leventhal

1

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Christina C Leslie

2

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Ira Tabas

3

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

language of work or name

0 references

publication date

24 November 2003

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

279

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

8084-8092

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Cell biology of atherosclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Cholesterol and phospholipid metabolism in macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Intracellular cholesterol transport.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Niemann-Pick C heterozygosity confers resistance to lesional necrosis and macrophage apoptosis in murine atherosclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Macrophages deficient in CTP:Phosphocholine cytidylyltransferase-alpha are viable under normal culture conditions but are highly susceptible to free cholesterol-induced death. Molecular genetic evidence that the induction of phosphatidylcholine bios

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Foam cell-forming J774 macrophages have markedly elevated acyl coenzyme A:cholesterol acyl transferase activity compared with mouse peritoneal macrophages in the presence of low density lipoprotein (LDL) despite similar LDL receptor activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Stimulation of CTP:phosphocholine cytidylyltransferase by free cholesterol loading of macrophages involves signaling through protein dephosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Distinct endosomal compartments in early trafficking of low density lipoprotein-derived cholesterol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Pharmacological inhibition of the intracellular transport of low-density lipoprotein-derived cholesterol in Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Niemann-Pick disease type C

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Accumulation of cholera toxin and GM1 ganglioside in the early endosome of Niemann-Pick C1-deficient cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Lipid changes in Niemann-Pick disease type C brain: personal experience and review of the literature

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Quantified increases of cholesterol, total lipid and globotriaosylceramide in filipin-positive Niemann-Pick type C fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Concurrent increase of cholesterol, sphingomyelin and glucosylceramide in the spleen from non-neurologic Niemann-Pick type C patients but also patients possibly affected with other lipid trafficking disorders

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

SREBPs: transcriptional mediators of lipid homeostasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Stimulation of vascular smooth muscle cell prostacyclin and prostaglandin E2 synthesis by plasma high and low density lipoproteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Differential low density lipoprotein receptor-dependent formation of eicosanoids in human blood-derived monocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Suppression of human T-cell mitogenesis by prostaglandin. Existence of a prostaglandin-producing suppressor cell

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Prostaglandin E2 suppresses chemokine production in human macrophages through the EP4 receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Activation of the murine EP3 receptor for PGE2 inhibits cAMP production and promotes platelet aggregation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Interleukin 1: a mitogen for human vascular smooth muscle cells that induces the release of growth-inhibitory prostanoids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

The role of PPARs in atherosclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Free cholesterol loading of macrophages induces apoptosis involving the fas pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310672200

21 January 2018

Identifiers

10.1074/JBC.M310672200

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

ResearchGate publication ID

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