(Q44683481)

English

Binding of the factor IX gamma-carboxyglutamic acid domain to the vitamin K-dependent gamma-glutamyl carboxylase active site induces an allosteric effect that may ensure processive carboxylation and regulate the release of carboxylated product

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 December 2017

Binding of the factor IX gamma-carboxyglutamic acid domain to the vitamin K-dependent gamma-glutamyl carboxylase active site induces an allosteric effect that may ensure processive carboxylation and regulate the release of carboxylated product (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

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author name string

Pen-Jen Lin

1

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

David L Straight

2

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Darrel W Stafford

3

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

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publication date

2 December 2003

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Europe PubMed Central

PubMed publication ID

5 December 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

5 December 2017

279

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Europe PubMed Central

PubMed publication ID

5 December 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

6560-6566

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Comparison of amino acid sequence of bovine coagulation Factor IX (Christmas Factor) with that of other vitamin K-dependent plasma proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

Vitamin K-Dependent Formation of γ-Carboxyglutamic Acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

Tethered processivity of the vitamin K-dependent carboxylase: factor IX is efficiently modified in a mechanism which distinguishes Gla's from Glu's and which accounts for comprehensive carboxylation in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

Processive post-translational modification. Vitamin K-dependent carboxylation of a peptide substrate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

A mutation in the propeptide of Factor IX leads to warfarin sensitivity by a novel mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

Missense mutations at ALA-10 in the factor IX propeptide: an insignificant variant in normal life but a decisive cause of bleeding during oral anticoagulant therapy.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

Enhanced gamma-carboxylation of recombinant factor X using a chimeric construct containing the prothrombin propeptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

Molecular cloning of matrix Gla protein: implications for substrate recognition by the vitamin K-dependent gamma-carboxylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

The gamma-carboxylation recognition site is sufficient to direct vitamin K-dependent carboxylation on an adjacent glutamate-rich region of thrombin in a propeptide-thrombin chimera.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

A novel fluorescence assay to study propeptide interaction with gamma-glutamyl carboxylase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

Vitamin K-dependent carboxylase: influence of the "propeptide" region on enzyme activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

Carboxylase overexpression effects full carboxylation but poor release and secretion of factor IX: implications for the release of vitamin K-dependent proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

Lipid-protein interactions in blood coagulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

Role of the propeptide and gamma-glutamic acid domain of factor IX for in vitro carboxylation by the vitamin K-dependent carboxylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

Role of the hexapeptide disulfide loop present in the gamma-carboxyglutamic acid domain of human protein C in its activation properties and in the in vitro anticoagulant activity of activated protein C

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

Localization of labile posttranslational modifications by electron capture dissociation: the case of gamma-carboxyglutamic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

The propeptides of the vitamin K-dependent proteins possess different affinities for the vitamin K-dependent carboxylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

The putative vitamin K-dependent gamma-glutamyl carboxylase internal propeptide appears to be the propeptide binding site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

Statistical determination of the average values of the extinction coefficients of tryptophan and tyrosine in native proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312239200

21 January 2018

Identifiers

10.1074/JBC.M312239200

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

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