(Q44691529)

English

Peroxynitrite irreversibly inactivates the human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1) in human breast cancer cells: a cellular and mechanistic study

scientific article published on 11 December 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 December 2017

Peroxynitrite irreversibly inactivates the human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1) in human breast cancer cells: a cellular and mechanistic study (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

author name string

Julien Dairou

1

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Noureddine Atmane

2

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Fernando Rodrigues-Lima

3

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Jean-Marie Dupret

4

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

language of work or name

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publication date

11 December 2003

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Europe PubMed Central

PubMed publication ID

5 December 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

5 December 2017

279

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Europe PubMed Central

PubMed publication ID

5 December 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

7708-7714

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Pharmacogenetics of the arylamine N-acetyltransferases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

The pharmacogenetics of NAT: structural aspects.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

An update on genetic, structural and functional studies of arylamine N-acetyltransferases in eucaryotes and procaryotes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Arylamine N-acetyltransferases and drug response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Skeletal Muscles Express the Xenobiotic-metabolizing Enzyme ArylamineN-acetyltransferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

NAT--from bugs to brains. An overview of the 2nd International Workshop on the arylamine N-acetyltransferases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Structure of arylamine N-acetyltransferase reveals a catalytic triad

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

3D model of human arylamine N-acetyltransferase 2: structural basis of the slow acetylator phenotype of the R64Q variant and analysis of the active-site loop.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

The structure of arylamine N-acetyltransferase from Mycobacterium smegmatis--an enzyme which inactivates the anti-tubercular drug, isoniazid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

NMR investigation of the catalytic mechanism of arylamine N-acetyltransferase from Salmonella typhimurium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Redox regulation of the human xenobiotic metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1). Reversible inactivation by hydrogen peroxide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

The inactivation mechanism of low molecular weight phosphotyrosine-protein phosphatase by H2O2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Reversible inactivation of the tumor suppressor PTEN by H2O2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Inhibition of cathepsin K by nitric oxide donors: evidence for the formation of mixed disulfides and a sulfenic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Multiple roles of cysteine in biocatalysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Nitric oxide: a unique endogenous signaling molecule in vascular biology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Peroxynitrite: reactive, invasive and enigmatic

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

NO: an inhibitor of cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Rapid and irreversible inhibition of creatine kinase by peroxynitrite

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Inhibition of caspase-3 by S-nitrosation and oxidation caused by nitric oxide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Mutation of tyrosine 190 to alanine eliminates the inactivation of cytochrome P450 2B1 by peroxynitrite

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Inactivation of glutathione S-transferases by nitric oxide-derived oxidants: exploring a role for tyrosine nitration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Peroxynitrite reactions and formation in mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Reactive nitrogen species in colon carcinogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Evidence of in vivo peroxynitrite formation in patients with colorectal carcinoma, higher plasma nitrate/nitrite levels, and lower protection against oxygen free radicals.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Association between nitrotyrosine levels and microvascular density in human breast cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Purification, characterization, and crystallization of an N-hydroxyarylamine O-acetyltransferase from Salmonella typhimurium.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

The COOH terminus of arylamine N-acetyltransferase from Salmonella typhimurium controls enzymic activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

The peroxynitrite generator, SIN-1, becomes a nitric oxide donor in the presence of electron acceptors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Peroxynitrite-induced inhibition and nitration of cardiac myofibrillar creatine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Mitochondrial creatine kinase is a prime target of peroxynitrite-induced modification and inactivation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Nitrosylation. the prototypic redox-based signaling mechanism.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Irreversible inactivation of magnesium-dependent neutral sphingomyelinase 1 (NSM1) by peroxynitrite, a nitric oxide-derived oxidant

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Reversible inhibition of the human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 by S-nitrosothiols

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Peroxynitrite-mediated stress is associated with proliferation of human metastatic colorectal carcinoma in the liver

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Cell signalling and the glutathione redox system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Inflammation and cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Inflammatory response: an unrecognised source of variability in the pharmacokinetics and pharmacodynamics of cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311469200

21 January 2018

Identifiers

10.1074/JBC.M311469200

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

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