(Q44699204)

20202594

5 December 2017

title

B-cell biology and related therapies in systemic lupus erythematosus (English)

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systemic lupus erythematosus

5 December 2017

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author name string

Sadia Ahmed

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6555414&resulttype=core&format=json

14 May 2020

Jennifer H Anolik

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6555414&resulttype=core&format=json

14 May 2020

publication date

1 February 2010

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20202594

Rheumatic Diseases Clinics of North America

5 December 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6555414&resulttype=core&format=json

14 May 2020

volume

36

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6555414&resulttype=core&format=json

14 May 2020

issue

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6555414&resulttype=core&format=json

14 May 2020

page(s)

109-30, viii-ix

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6555414&resulttype=core&format=json

A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus

14 May 2020

cites work

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12 December 2020

Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations

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12 December 2020

TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease

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12 December 2020

The combination of apoptotic U937 cells and lupus IgG is a potent IFN-alpha inducer

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12 December 2020

Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis

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12 December 2020

Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus

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12 December 2020

Reciprocal regulation of polarized cytokine production by effector B and T cells

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12 December 2020

Cutting edge: reversal of murine lupus nephritis with CTLA4Ig and cyclophosphamide

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12 December 2020

Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus.

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12 December 2020

Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance

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12 December 2020

A pivotal role for the natural interferon alpha-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus

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12 December 2020

Rituximab: mechanism of action and resistance

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12 December 2020

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

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12 December 2020

Can morbidity and mortality of SLE be improved?

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12 December 2020

The effect of anti-CD40 ligand antibody on B cells in human systemic lupus erythematosus

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12 December 2020

Rituximab treatment results in impaired secondary humoral immune responsiveness.

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12 December 2020

B cells regulate autoimmunity by provision of IL-10.

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12 December 2020

Treatment of systemic lupus erythematosus by inhibition of T cell costimulation with anti-CD154: a randomized, double-blind, placebo-controlled trial

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12 December 2020

Rituximab for the treatment of refractory autoimmune hemolytic anemia in children

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12 December 2020

Effects of anti-CD154 treatment on B cells in murine systemic lupus erythematosus

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12 December 2020

Prevention of arthritis by interleukin 10-producing B cells

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12 December 2020

A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis

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12 December 2020

Correlation between circulating CD27high plasma cells and disease activity in patients with systemic lupus erythematosus

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12 December 2020

Isolated lymphoid follicle formation is inducible and dependent upon lymphotoxin-sufficient B lymphocytes, lymphotoxin beta receptor, and TNF receptor I function

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12 December 2020

Serologic changes following B lymphocyte depletion therapy for rheumatoid arthritis

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12 December 2020

Predominant autoantibody production by early human B cell precursors

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12 December 2020

Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6

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12 December 2020

Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG

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12 December 2020

Development of Autoantibodies before the Clinical Onset of Systemic Lupus Erythematosus

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12 December 2020

Activation of autoreactive B cells by CpG dsDNA

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12 December 2020

B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: longitudinal observations.

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12 December 2020

Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF.

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12 December 2020

Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice

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12 December 2020

B cell abnormalities in systemic lupus erythematosus

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12 December 2020

Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches.

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12 December 2020

Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes.

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12 December 2020

B cell depletion as a novel treatment for systemic lupus erythematosus: a phase I/II dose-escalation trial of rituximab

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12 December 2020

Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus

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12 December 2020

B cells alter the phenotype and function of follicular-homing CXCR5+ T cells

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12 December 2020

The inhibitory Fcγ receptor modulates autoimmunity by limiting the accumulation of immunoglobulin G+ anti-DNA plasma cells

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12 December 2020

Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy

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12 December 2020

Rituximab inhibits the in vivo primary and secondary antibody response to a neoantigen, bacteriophage phiX174.

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12 December 2020

Induction of remission by B lymphocyte depletion in eleven patients with refractory antineutrophil cytoplasmic antibody-associated vasculitis

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12 December 2020

Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.

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12 December 2020

Restoration of tolerance in lupus by targeted inhibitory receptor expression

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12 December 2020

Remission of proliferative lupus nephritis following B cell depletion therapy is preceded by down-regulation of the T cell costimulatory molecule CD40 ligand: an open-label trial.

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12 December 2020

Defective B cell tolerance checkpoints in systemic lupus erythematosus

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12 December 2020

Network communications: lymphotoxins, LIGHT, and TNF.

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12 December 2020

Plasmacytoid dendritic cells control TLR7 sensitivity of naive B cells via type I IFN.

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12 December 2020

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

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12 December 2020

Regeneration of the immunoglobulin heavy-chain repertoire after transient B-cell depletion with an anti-CD20 antibody

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12 December 2020

Rituximab anti-B-cell therapy in systemic lupus erythematosus: pointing to the future

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12 December 2020

Loss of function of a lupus-associated FcγRIIb polymorphism through exclusion from lipid rafts

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12 December 2020

Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus.

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12 December 2020

Immunotherapy using unconjugated CD19 monoclonal antibodies in animal models for B lymphocyte malignancies and autoimmune disease

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12 December 2020

A checkpoint for autoreactivity in human IgM+ memory B cell development

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12 December 2020

TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE.

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12 December 2020

Circulating levels of B lymphocyte stimulator in patients with rheumatoid arthritis following rituximab treatment: relationships with B cell depletion, circulating antibodies, and clinical relapse

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12 December 2020

B cell immunobiology in disease: evolving concepts from the clinic

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12 December 2020

Clinical and immunological effects of Rituximab in patients with lupus nephritis refractory to conventional therapy: a pilot study

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12 December 2020

Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication

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12 December 2020

Space, selection, and surveillance: setting boundaries with BLyS.

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12 December 2020

Rituximab therapy for childhood-onset systemic lupus erythematosus

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12 December 2020

Regulation of B cell tolerance by the lupus susceptibility gene Ly108.

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12 December 2020

Clinical trial design in systemic lupus erythematosus

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12 December 2020

Selective dysregulation of the FcgammaIIB receptor on memory B cells in SLE

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12 December 2020

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

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12 December 2020

Early effects of rituximab on the synovial cell infiltrate in patients with rheumatoid arthritis

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12 December 2020

B cell regulation of CD4+CD25+ T regulatory cells and IL-10 via B7 is essential for recovery from experimental autoimmune encephalomyelitis

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12 December 2020

Histopathologic and clinical outcome of rituximab treatment in patients with cyclophosphamide-resistant proliferative lupus nephritis

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12 December 2020

Safety, pharmacokinetics and pharmacodynamics of atacicept in healthy volunteers

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12 December 2020

A new population of cells lacking expression of CD27 represents a notable component of the B cell memory compartment in systemic lupus erythematosus

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12 December 2020

Cutting edge: primary B lymphocytes preferentially expand allogeneic FoxP3+ CD4 T cells

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12 December 2020

Delayed memory B cell recovery in peripheral blood and lymphoid tissue in systemic lupus erythematosus after B cell depletion therapy

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12 December 2020

Treatment of refractory SLE with rituximab plus cyclophosphamide: clinical effects, serological changes, and predictors of response

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12 December 2020

Reduced B lymphocyte and immunoglobulin levels after atacicept treatment in patients with systemic lupus erythematosus: results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating trial

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12 December 2020

Safety and efficacy of additional courses of rituximab in patients with active rheumatoid arthritis: An open-label extension analysis

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12 December 2020

Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice

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12 December 2020

The effects of rituximab on immunocompetency in patients with autoimmune disease

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12 December 2020

Risk of serious infections during rituximab, abatacept and anakinra treatments for rheumatoid arthritis: meta-analyses of randomised placebo-controlled trials

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12 December 2020

Variability in the biological response to anti-CD20 B cell depletion in systemic lupus erythaematosus

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12 December 2020

The human spleen is a major reservoir for long-lived vaccinia virus-specific memory B cells

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12 December 2020

TLR-activated B cells suppress T cell-mediated autoimmunity

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12 December 2020

Longterm clinical and immunological effects of anti-CD20 treatment in patients with refractory systemic lupus erythematosus.

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12 December 2020

Cytokine-producing B lymphocytes-key regulators of immunity

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12 December 2020

Not always the bad guys: B cells as regulators of autoimmune pathology

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12 December 2020

Clinical trials in systemic lupus erythematosus (SLE): lessons from the past as we proceed to the future--the EULAR recommendations for the management of SLE and the use of end-points in clinical trials

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12 December 2020

B lymphocyte stimulator regulates adaptive immune responses by directly promoting dendritic cell maturation

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12 December 2020

Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: delineation by expression of CD27, IgD, and CD95

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12 December 2020

The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis

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12 December 2020

T cell-independent and toll-like receptor-dependent antigen-driven activation of autoreactive B cells

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12 December 2020

New therapies in systemic lupus erythematosus - trials, troubles and tribulations.... working towards a solution

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12 December 2020

Autoreactive B cells discriminate CpG-rich and CpG-poor DNA and this response is modulated by IFN-alpha

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12 December 2020

ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity

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12 December 2020

Safety of biological therapies following rituximab treatment in rheumatoid arthritis patients

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12 December 2020

HLA-DRhigh/CD27high plasmablasts indicate active disease in patients with systemic lupus erythematosus.

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12 December 2020

Rituximab in severe lupus nephritis: early B-cell depletion affects long-term renal outcome

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12 December 2020

Novel human transitional B cell populations revealed by B cell depletion therapy

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12 December 2020

Is combination rituximab with cyclophosphamide better than rituximab alone in the treatment of lupus nephritis?

1 reference

12 December 2020

Rituximab in systemic lupus erythematosus: A systematic review of off-label use in 188 cases

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12 December 2020

Translational Mini-Review Series on B Cell-Directed Therapies: Recent advances in B cell-directed biological therapies for autoimmune disorders

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12 December 2020

Rituximab is an effective treatment for lupus nephritis and allows a reduction in maintenance steroids.

1 reference

12 December 2020

Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a Review from the Research on Adverse Drug Events and Reports (RADAR) Project

1 reference

12 December 2020

A perspective on B-cell-targeting therapy for SLE.

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12 December 2020

Therapy: rituximab and PML risk-informed decisions needed!

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12 December 2020

Prolonged effects of short-term anti-CD20 B cell depletion therapy in murine systemic lupus erythematosus

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12 December 2020

Two negative randomized controlled trials in lupus: now what?

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12 December 2020

CD20: a regulator of cell-cycle progression of B lymphocytes

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12 December 2020

The role of B cells in lpr/lpr-induced autoimmunity

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12 December 2020

B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events

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12 December 2020

10.1016/J.RDC.2009.12.002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6555414&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6555414&resulttype=core&format=json

14 May 2020

20202594

1 reference