(Q44728755)

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Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase.

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scholarly article

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14724257%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase (English)

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14724257%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

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Michael R. Duchen

3

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14724257%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

Andrey Y. Abramov

1

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14724257%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

author name string

Laura Canevari

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14724257%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

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publication date

1 January 2004

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14724257%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

Journal of Neuroscience

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14724257%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

24

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14724257%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14724257%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

565-575

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14724257%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial abnormalities in neuroectodermal cells stably expressing human amyloid precursor protein (hAPP751)

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depolarization of in situ mitochondria due to hydrogen peroxide-induced oxidative stress in nerve terminals: inhibition of alpha-ketoglutarate dehydrogenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of Oxidative Stress on the Impairment of Energy Metabolism Induced by Aβ Peptides on PC12 Cells: Protection by Antioxidants

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate-induced mitochondrial depolarisation and perturbation of calcium homeostasis in cultured rat hippocampal neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid fragment 25-35 selectively decreases complex IV activity in isolated mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of NADPH oxidase in Alzheimer's disease brains.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversible inactivation of superoxide-sensitive aconitase in Abeta1-42-treated neuronal cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial intermembrane junctional complexes and their role in cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria and calcium: from cell signalling to cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploration of the role of reactive oxygen species in glutamate neurotoxicity in rat hippocampal neurones in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxic Abeta peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial abnormalities in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta protein forms ion channels: implications for Alzheimer's disease pathophysiology

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative imaging of glutathione in hippocampal neurons and glia in culture using monochlorobimane

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free radicals in the physiological control of cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of cytochrome c-mediated apoptosis by amyloid beta 25-35 requires functional mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Amyloid neurotoxicity is exacerbated during glycolysis inhibition and mitochondrial impairment in the rat hippocampus in vivo and in isolated nerve terminals: implications for Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of amyloid beta-peptide on permeability transition pore: a comparative study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of beta-amyloid peptide fragment 25-35 on nonselective permeability of mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-amyloid fragment 25-35 causes mitochondrial dysfunction in primary cortical neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta peptide induces cytochrome C release from isolated mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative mitochondrial membrane potential and [Ca2+]i in type I cells isolated from the rabbit carotid body

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of oxidative abnormalities in the pathophysiology of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel metal-free low molecular weight superoxide dismutase mimic.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitroxide stable radical prevents primaquine-induced lysis of red blood cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transfer of beta-amyloid precursor protein gene using adenovirus vector causes mitochondrial abnormalities in cultured normal human muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial deenergization underlies neuronal calcium overload following a prolonged glutamate challenge

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium homeostasis and reactive oxygen species production in cells transformed by mitochondria from individuals with sporadic Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.4042-03.2004

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14724257%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14724257%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14724257%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

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