(Q44728787)

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Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric Drosophila enzyme.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14724274%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric Drosophila enzyme (English)

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Europe PubMed Central

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17 November 2019

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Orsolya Barabas

2

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17 November 2019

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Júlia Kovári

1

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17 November 2019

Enikõ Takács

3

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17 November 2019

Angéla Békési

4

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17 November 2019

Zsófia Dubrovay

5

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17 November 2019

Veronika Pongrácz

6

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17 November 2019

Imre Zagyva

7

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17 November 2019

Timea Imre

8

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17 November 2019

Pál Szabó

9

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17 November 2019

Beáta G Vértessy

10

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17 November 2019

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14 January 2004

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17 November 2019

Journal of Biological Chemistry

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17 November 2019

279

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17 November 2019

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17 November 2019

17932-17944

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17 November 2019

Kinetic characterization of dUTPase from Escherichia coli.

1 reference

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21 January 2018

Transient accumulation of Okazaki fragments as a result of uracil incorporation into nascent DNA

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Lethality of a dut (deoxyuridine triphosphatase) mutation in Escherichia coli

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Increased mutation frequency of feline immunodeficiency virus lacking functional deoxyuridine-triphosphatase

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Novel gain of function activity of p53 mutants: activation of the dUTPase gene expression leading to resistance to 5-fluorouracil

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Control of Drosophila deoxyuridine triphosphatase. Existence of a developmentally expressed protein inhibitor

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21 January 2018

Identification of a consensus cyclin-dependent kinase phosphorylation site unique to the nuclear form of human deoxyuridine triphosphate nucleotidohydrolase

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21 January 2018

Characterization of distinct nuclear and mitochondrial forms of human deoxyuridine triphosphate nucleotidohydrolase

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21 January 2018

The human dUTPase gene encodes both nuclear and mitochondrial isoforms. Differential expression of the isoforms and characterization of a cDNA encoding the mitochondrial species

1 reference

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21 January 2018

Identification of sequence determinants of human nuclear dUTPase isoform localization

1 reference

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21 January 2018

Human dUTP pyrophosphatase: uracil recognition by a beta hairpin and active sites formed by three separate subunits

1 reference

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21 January 2018

Crystal structure of dUTP pyrophosphatase from feline immunodeficiency virus

1 reference

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21 January 2018

Crystal structure of a dUTPase

1 reference

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21 January 2018

Crystal structure of dUTPase from equine infectious anaemia virus; active site metal binding in a substrate analogue complex

1 reference

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21 January 2018

Crystal structure of the Escherichia coli dUTPase in complex with a substrate analogue (dUDP)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313643200

21 January 2018

Altered subunit communication in subfamilies of trimeric dUTPases

1 reference

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21 January 2018

Flexible glycine rich motif of Escherichia coli deoxyuridine triphosphate nucleotidohydrolase is important for functional but not for structural integrity of the enzyme

1 reference

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21 January 2018

The C-terminus of dUTPase: observation on flexibility using NMR.

1 reference

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21 January 2018

dUTPase from Escherichia coli; high-level expression and one-step purification.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313643200

21 January 2018

Use of T7 RNA polymerase to direct expression of cloned genes

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21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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21 January 2018

Specific derivatization of the active site tyrosine in dUTPase perturbs ligand binding to the active site

1 reference

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21 January 2018

dUTPase and nucleocapsid polypeptides of the Mason-Pfizer monkey virus form a fusion protein in the virion with homotrimeric organization and low catalytic efficiency

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21 January 2018

Identification of tyrosine as a functional residue in the active site of Escherichia coli dUTPase.

1 reference

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21 January 2018

Catalytic and structural role of the metal ion in dUTP pyrophosphatase

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Insect glycobiology: a lectin multigene family in Drosophila melanogaster

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Nup154, a new Drosophila gene essential for male and female gametogenesis is related to the nup155 vertebrate nucleoporin gene.

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21 January 2018

Physiological concentrations of purines and pyrimidines

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Methods to estimate the conformation of proteins and polypeptides from circular dichroism data

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Evaluation of secondary structure of proteins from UV circular dichroism spectra using an unsupervised learning neural network.

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Kinetic properties and stereospecificity of the monomeric dUTPase from herpes simplex virus type 1.

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Cloning and identification of rat deoxyuridine triphosphatase as an inhibitor of peroxisome proliferator-activated receptor alpha

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The geometry of metal-ligand interactions relevant to proteins.

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Identifiers

10.1074/JBC.M313643200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14724274%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14724274%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

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