(Q44732797)

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Construction of recombinant targeting immunogens incorporating an HIV-1 neutralizing epitope into sites of differing conformational constraint

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Europe PubMed Central

PubMed publication ID

5 December 2017

Construction of recombinant targeting immunogens incorporating an HIV-1 neutralizing epitope into sites of differing conformational constraint (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

author name string

Jason Ho

1

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Kelly S MacDonald

2

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Europe PubMed Central

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5 December 2017

Brian H Barber

3

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Europe PubMed Central

PubMed publication ID

5 December 2017

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publication date

1 January 2002

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Europe PubMed Central

PubMed publication ID

5 December 2017

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

20

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Europe PubMed Central

PubMed publication ID

5 December 2017

7-8

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

1169-1180

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

Recombinant human monoclonal antibody IgG1b12 neutralizes diverse human immunodeficiency virus type 1 primary isolates

1 reference

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AIDS and HIV vaccines

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Generation of Human Monoclonal Antibodies against HIV-1 Proteins; Electrofusion and Epstein-Barr Virus Transformation for Peripheral Blood Lymphocyte Immortalization

1 reference

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Immunogenic presentation of a conserved gp41 epitope of human immunodeficiency virus type 1 on recombinant surface antigen of hepatitis B virus.

1 reference

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Epitope insertion into variable loops of HIV-1 gp120 as a potential means to improve immunogenicity of viral envelope protein

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Antigenicity and immunogenicity of the HIV-1 gp41 epitope ELDKWA inserted into permissive sites of the MalE protein

1 reference

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Adjuvant-independent immunization by immunotargeting antigens to MHc and non-MHc determinants in vivo

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Adjuvant-independent induction of immune responses by antibody-mediated targeting of protein and peptide antigens

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The immunotargeting approach to adjuvant-independent immunization with influenza haemagglutinin

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Adhesion-mediated enhancement of the adjuvant activity of alum

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The immunotargeting approach to adjuvant-independent subunit vaccine design

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Intranasal antigen targeting to MHC class II molecules primes local IgA and serum IgG antibody responses in mice

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Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies

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Cross-reaction of a monoclonal antibody to human MHC class II molecules with rabbit B cells

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Conformational changes in cell surface HIV-1 envelope glycoproteins are triggered by cooperation between cell surface CD4 and co-receptors

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CD4-Induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: consequences for virus entry and neutralization

1 reference

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Sequential CD4-coreceptor interactions in human immunodeficiency virus type 1 Env function: soluble CD4 activates Env for coreceptor-dependent fusion and reveals blocking activities of antibodies against cryptic conserved epitopes on gp120.

1 reference

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Conformational changes of gp120 in epitopes near the CCR5 binding site are induced by CD4 and a CD4 miniprotein mimetic

1 reference

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

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Two interaction modes of the gp41-derived peptides with gp41 and their correlation with antimembrane fusion activity

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Inhibiting HIV-1 entry: discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket

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A general model for the transmembrane proteins of HIV and other retroviruses

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Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS.

1 reference

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Recombinant antibodies with conformationally constrained HIV type 1 epitope inserts elicit glycoprotein 160-specific antibody responses in vivo

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Major histocompatibility complex class I-restricted presentation of influenza virus nucleoprotein peptide by B lymphoma cells harboring an antibody gene antigenized with the virus peptide

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Efficient loading of identical viral peptide onto class II molecules by antigenized immunoglobulin and influenza virus

1 reference

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Presentation of a Viral T Cell Epitope Expressed in the CDR3 Region of a Self Immunoglobulin Molecule

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Immunogenicity of an engineered internal image antibody

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Recombinant antibodies containing an engineered B-cell epitope capable of eliciting conformation-specific antibody responses

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Expression of an exogenous peptide epitope genetically engineered in the variable domain of an immunoglobulin: implications for antibody and peptide folding

1 reference

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Foreign peptides expressed in engineered chimeric self molecules

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Immunopotency of a viral peptide assembled on the carbohydrate moieties of self immunoglobulins

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Immunoglobulin as a vehicle for foreign antigenic peptides immunogenic to T cells

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Antibodies engineered with IgD specificity efficiently deliver integrated T-cell epitopes for antigen presentation by B cells

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Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

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Identifiers

10.1016/S0264-410X(01)00441-8

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

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