(Q44735605)

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Analytical solutions for (13)C isotopomer analysis of complex metabolic conditions: substrate oxidation, multiple pyruvate cycles, and gluconeogenesis

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Europe PubMed Central

PubMed publication ID

5 December 2017

Analytical solutions for (13)C isotopomer analysis of complex metabolic conditions: substrate oxidation, multiple pyruvate cycles, and gluconeogenesis (English)

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Europe PubMed Central

PubMed publication ID

5 December 2017

gluconeogenesis

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author name string

A Dean Sherry

1

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Europe PubMed Central

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5 December 2017

F Mark H Jeffrey

2

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Europe PubMed Central

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5 December 2017

Craig R Malloy

3

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5 December 2017

publication date

1 January 2004

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5 December 2017

Metabolic Engineering

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5 December 2017

6

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5 December 2017

1

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Europe PubMed Central

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5 December 2017

12-24

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5 December 2017

Tracing hepatic gluconeogenesis relative to citric acid cycle activity in vitro and in vivo. Comparisons in the use of [3-13C]lactate, [2-13C]acetate, and alpha-keto[3-13C]isocaproate

1 reference

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Applications of mass isotopomer analysis to nutrition research

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Quantification of gluconeogenesis in cirrhosis: response to glucagon

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Quantifying gluconeogenesis during fasting.

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Metabolic compartmentation of lactate in the glucose-perfused rat heart

1 reference

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Pyruvate carboxylase and propionyl-CoA carboxylase as anaplerotic enzymes in skeletal muscle mitochondria

1 reference

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Isotopomer analysis of citric acid cycle and gluconeogenesis in rat liver. Reversibility of isocitrate dehydrogenase and involvement of ATP-citrate lyase in gluconeogenesis

1 reference

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Non-invasive tracing of liver intermediary metabolism in normal subjects and in moderately hyperglycaemic NIDDM subjects. Evidence against increased gluconeogenesis and hepatic fatty acid oxidation in NIDDM

1 reference

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Modeling of liver citric acid cycle and gluconeogenesis based on 13C mass isotopomer distribution analysis of intermediates

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13C-NMR: a simple yet comprehensive method for analysis of intermediary metabolism

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13C isotopomer model for estimation of anaplerotic substrate oxidation via acetyl-CoA.

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13C isotopomer analysis of glutamate by tandem mass spectrometry.

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Sources of acetyl-CoA entering the tricarboxylic acid cycle as determined by analysis of succinate 13C isotopomers

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Determination of gluconeogenesis in vivo with 14C-labeled substrates

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Analysis of tricarboxylic acid cycle using [14C]citrate specific activity ratios.

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Gluconeogenesis from labeled carbon: estimating isotope dilution.

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Estimating gluconeogenesis with [U-13C]glucose: molecular condensation requires a molecular approach

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Model equations for condensation biosynthesis using stable isotopes and radioisotopes

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14C-labeled propionate metabolism in vivo and estimates of hepatic gluconeogenesis relative to Krebs cycle flux

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Pyruvate and lactate metabolism in the in vivo dog heart

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Metabolic heterogeneity of carbon substrate utilization in mammalian heart: NMR determinations of mitochondrial versus cytosolic compartmentation

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Carbon flux through citric acid cycle pathways in perfused heart by 13C NMR spectroscopy.

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Analysis of tricarboxylic acid cycle of the heart using 13C isotope isomers

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Contribution of exogenous substrates to acetyl coenzyme A: measurement by 13C NMR under non-steady-state conditions

1 reference

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The flux of pyruvate in perfused rat heart

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The effect of insulin and growth hormone on the flux of tracer from labelled lactate in perfused rat heart

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Pyruvate carboxylation as an anaplerotic mechanism in the isolated perfused rat heart

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Metabolic compartmentation of pyruvate in the isolated perfused rat heart

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Propionate metabolism in the rat heart by 13C n.m.r. spectroscopy.

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Alterations in substrate utilization in the reperfused myocardium: a direct analysis by 13C NMR

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Gluconeogenesis in very low birth weight infants receiving total parenteral nutrition

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Conversion of fatty acids to carbohydrate; application of isotopes to this problem and role of the Krebs cycle as a synthetic pathway

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Identifiers

10.1016/J.YMBEN.2003.10.007

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

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