(Q44735758)

English

Systematic mutagenesis of the leucine-rich repeat (LRR) domain of CCR4 reveals specific sites for binding to CAF1 and a separate critical role for the LRR in CCR4 deadenylase activity

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Europe PubMed Central

PubMed publication ID

5 December 2017

Systematic mutagenesis of the leucine-rich repeat (LRR) domain of CCR4 reveals specific sites for binding to CAF1 and a separate critical role for the LRR in CCR4 deadenylase activity (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

author name string

Lisa B Clark

1

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Europe PubMed Central

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5 December 2017

Palaniswamy Viswanathan

2

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5 December 2017

Gloria Quigley

3

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Europe PubMed Central

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5 December 2017

Yueh-Chin Chiang

4

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Europe PubMed Central

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5 December 2017

Jeffrey S McMahon

5

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Europe PubMed Central

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5 December 2017

Gang Yao

6

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Europe PubMed Central

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5 December 2017

Junji Chen

7

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Europe PubMed Central

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5 December 2017

Andreas Nelsbach

8

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5 December 2017

Clyde L Denis

9

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Europe PubMed Central

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5 December 2017

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publication date

20 January 2004

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Europe PubMed Central

PubMed publication ID

5 December 2017

number of pages

8

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Journal of Biological Chemistry

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5 December 2017

279

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5 December 2017

14

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Europe PubMed Central

PubMed publication ID

5 December 2017

13616-13623

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Europe PubMed Central

PubMed publication ID

5 December 2017

CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Functionally unrelated signalling proteins contain a fold similar to Mg2+-dependent endonucleases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

The CCR4-NOT complex plays diverse roles in mRNA metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Mutations affecting stability and deadenylation of the yeast MFA2 transcript

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Identification of a mouse protein whose homolog in Saccharomyces cerevisiae is a component of the CCR4 transcriptional regulatory complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Identification of four families of yCCR4- and Mg2+-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

DBF2, a cell cycle-regulated protein kinase, is physically and functionally associated with the CCR4 transcriptional regulatory complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

The leucine-rich repeat: a versatile binding motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Proteins with leucine-rich repeats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Molecular recognition of human angiogenin by placental ribonuclease inhibitor--an X-ray crystallographic study at 2.0 A resolution.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: purification, biochemical characterization, and identification of a leucine-rich repeat motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Crystal structure of the spliceosomal U2B"-U2A' protein complex bound to a fragment of U2 small nuclear RNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Structure of the lnlB leucine-rich repeats, a domain that triggers host cell invasion by the bacterial pathogen L. monocytogenes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Unusual molecular architecture of the Yersinia pestis cytotoxin YopM: a leucine-rich repeat protein with the shortest repeating unit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Site-specific mutagenesis reveals differences in the structural bases for tight binding of RNase inhibitor to angiogenin and RNase A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

The specificity of polygalacturonase-inhibiting protein (PGIP): a single amino acid substitution in the solvent-exposed beta-strand/beta-turn region of the leucine-rich repeats (LRRs) confers a new recognition capability.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

F-box protein Grr1 interacts with phosphorylated targets via the cationic surface of its leucine-rich repeat

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

CCR4 is a glucose-regulated transcription factor whose leucine-rich repeat binds several proteins important for placing CCR4 in its proper promoter context

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Dissection of the ADR1 protein reveals multiple, functionally redundant activation domains interspersed with inhibitory regions: evidence for a repressor binding to the ADR1c region

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Identification of multiple RNA features that influence CCR4 deadenylation activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Determinants in nuclease specificity of Ape1 and Ape2, human homologues of Escherichia coli exonuclease III.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Nocturnin, a deadenylase in Xenopus laevis retina: a mechanism for posttranscriptional control of circadian-related mRNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

A structural basis of the interactions between leucine-rich repeats and protein ligands

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Determination of residues important in hormone binding to the extracellular domain of the luteinizing hormone/chorionic gonadotropin receptor by site-directed mutagenesis and modeling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Structure, function and evolution of plant disease resistance genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Structural diversity of leucine-rich repeat proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313202200

21 January 2018

Identifiers

10.1074/JBC.M313202200

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 December 2017

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