(Q44782012)

6 December 2017

title

Impaired activation of phosphatidylinositol 3-kinase by leptin is a novel mechanism of hepatic leptin resistance in diet-induced obesity (English)

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6 December 2017

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Wan Huang

1

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6 December 2017

Nikolas Dedousis

series ordinal

2

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6 December 2017

Bankim A Bhatt

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3

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6 December 2017

Robert M O'Doherty

series ordinal

4

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6 December 2017

language of work or name

English

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publication date

1 March 2004

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Journal of Biological Chemistry

6 December 2017

number of pages

6

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based on heuristic

inferred from page(s)

published in

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6 December 2017

volume

279

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6 December 2017

issue

21

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6 December 2017

page(s)

21695-21700

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The physiology of cellular liporegulation

6 December 2017

cites work

1 reference

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21 January 2018

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Weight-reducing effects of the plasma protein encoded by the obese gene

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Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy.

21 January 2018

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Effect of leptin replacement on intrahepatic and intramyocellular lipid content in patients with generalized lipodystrophy

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Direct antidiabetic effect of leptin through triglyceride depletion of tissues.

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Disappearance of body fat in normal rats induced by adenovirus-mediated leptin gene therapy

21 January 2018

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Leptin selectively decreases visceral adiposity and enhances insulin action.

21 January 2018

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Liporegulation in diet-induced obesity. The antisteatotic role of hyperleptinemia

21 January 2018

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Muscle triglyceride and insulin resistance

21 January 2018

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Metabolic complications of obesity

21 January 2018

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Triglycerides, fatty acids and insulin resistance--hyperinsulinemia

21 January 2018

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Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes

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Force generation, but not myosin ATPase activity, declines with age in rat muscle fibers

21 January 2018

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Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

21 January 2018

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The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

21 January 2018

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Acute intravenous leptin infusion increases glucose turnover but not skeletal muscle glucose uptake in ob/ob mice

21 January 2018

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Overfeeding rapidly induces leptin and insulin resistance

21 January 2018

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The isolated perfused rat liver: conceptual and practical considerations

21 January 2018

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Nutritional regulation of hypothalamic leptin receptor gene expression is defective in diet-induced obesity

21 January 2018

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In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: overlapping but distinct pathways from insulin

21 January 2018

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Leptin and tumor necrosis factor-alpha induce the tyrosine phosphorylation of signal transducer and activator of transcription proteins in the hypothalamus of normal rats in vivo

21 January 2018

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Short-Term Leptin-Dependent Inhibition of Hepatic Gluconeogenesis Is Mediated by Insulin Receptor Substrate-2

21 January 2018

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Leptin inhibits insulin secretion by activation of phosphodiesterase 3B.

21 January 2018

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Physiological increase in plasma leptin markedly inhibits insulin secretion in vivo

21 January 2018

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Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

21 January 2018

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Leptin activates cardiac fatty acid oxidation independent of changes in the AMP-activated protein kinase-acetyl-CoA carboxylase-malonyl-CoA axis

21 January 2018

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Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

21 January 2018

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Identification of SOCS-3 as a potential mediator of central leptin resistance

21 January 2018

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PTP1B regulates leptin signal transduction in vivo

21 January 2018

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Attenuation of leptin action and regulation of obesity by protein tyrosine phosphatase 1B.

21 January 2018

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Peripheral metabolic actions of leptin

21 January 2018

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Localization of leptin receptor mRNA splice variants in murine peripheral tissues by RT-PCR and in situ hybridization

21 January 2018

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Hyperleptinemia depletes fat from denervated fat tissue

21 January 2018

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Comparing the hypothalamic and extrahypothalamic actions of endogenous hyperleptinemia

21 January 2018

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Selective deletion of leptin receptor in neurons leads to obesity

21 January 2018

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Acute stimulation of glucose metabolism in mice by leptin treatment

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M401546200

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6 December 2017

1 reference