(Q44795710)

6 December 2017

title

Architecture of the Alzheimer's A beta P ion channel pore (English)

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6 December 2017

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N Arispe

1

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6 December 2017

publication date

1 January 2004

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6 December 2017

number of pages

16

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Journal of Membrane Biology

inferred from page(s)

published in

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6 December 2017

volume

197

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6 December 2017

issue

1

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6 December 2017

page(s)

33-48

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Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

6 December 2017

cites work

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12 December 2020

Plaque busters: strategies to inhibit amyloid formation in Alzheimer's disease

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12 December 2020

Amyloid beta protein forms ion channels: implications for Alzheimer's disease pathophysiology

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Self-association of beta-amyloid peptide (1-40) in solution and binding to lipid membranes.

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Alzheimer's and prion disease as disorders of protein conformation: implications for the design of novel therapeutic approaches

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In vivo neurotoxicity of beta-amyloid [beta(1-40)] and the beta(25-35) fragment

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Theoretical models of the ion channel structure of amyloid beta-protein

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Electrophysiologic properties of channels induced by Abeta25-35 in planar lipid bilayers

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Amino-terminal Deletions Enhance Aggregation of β-Amyloid Peptides in Vitro

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Fresh and globular amyloid beta protein (1-42) induces rapid cellular degeneration: evidence for AbetaP channel-mediated cellular toxicity

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Alzheimer's disease: a cell biological perspective

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12 December 2020

Genetics and biology of the Alzheimer amyloid precursor

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12 December 2020

Characterization of Ca2(+)-dependent phospholipid binding, vesicle aggregation and membrane fusion by annexins

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12 December 2020

Selective inhibition of Abeta fibril formation

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12 December 2020

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

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12 December 2020

Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayer membranes

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12 December 2020

Displacement currents associated with the insertion of Alzheimer disease amyloid beta-peptide into planar bilayer membranes

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12 December 2020

Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation

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12 December 2020

beta-Amyloid increases choline conductance of PC12 cells: possible mechanism of toxicity in Alzheimer's disease

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Beta-sheet breaker peptide inhibitor of Alzheimer's amyloidogenesis with increased blood-brain barrier permeability and resistance to proteolytic degradation in plasma

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Amyloid plaque core protein in Alzheimer disease and Down syndrome

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Zn2+ interaction with Alzheimer amyloid beta protein calcium channels

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12 December 2020

Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs

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12 December 2020

Channel formation in planar lipid bilayers by a neurotoxic fragment of the beta-amyloid peptide

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In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

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12 December 2020

Alzheimer's disease: a central role for amyloid

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Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

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Lipid interaction differentiates the constitutive and stress-induced heat shock proteins Hsc70 and Hsp70.

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Amyloid beta protein-(1-42) forms calcium-permeable, Zn2+-sensitive channel

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Ionic effects of the Alzheimer's disease beta-amyloid precursor protein and its metabolic fragments

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Arrest of beta-amyloid fibril formation by a pentapeptide ligand

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Effect of beta amyloid peptides on neurons in hippocampal slice cultures

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12 December 2020

A strategy for designing inhibitors of beta-amyloid toxicity

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Amyloid beta peptides act directly on single neurons

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12 December 2020

Lipid binding to amyloid beta-peptide aggregates: preferential binding of cholesterol as compared with phosphatidylcholine and fatty acids

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12 December 2020

Vesicle Aggregation by Annexin I: Role of a Secondary Membrane Binding Site

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12 December 2020

Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy

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12 December 2020

Highly sensitive and stable phosphatidylserine liposome aggregation assay for annexins

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12 December 2020

Solution conformations and aggregational properties of synthetic amyloid beta-peptides of Alzheimer's disease. Analysis of circular dichroism spectra

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12 December 2020

Amyloid beta-peptide is produced by cultured cells during normal metabolism

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12 December 2020

The molecular pathology of Alzheimer's disease

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12 December 2020

beta-Amyloid Ca(2+)-channel hypothesis for neuronal death in Alzheimer disease

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12 December 2020

Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum

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12 December 2020

beta-Amyloid peptide decreases membrane fluidity.

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12 December 2020

Amyloid peptide channels: blockade by zinc and inhibition by Congo red (amyloid channel block).

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12 December 2020

Amyloid beta protein-induced irreversible current in rat cortical neurones

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12 December 2020

Fresh and nonfibrillar amyloid beta protein(1-40) induces rapid cellular degeneration in aged human fibroblasts: evidence for AbetaP-channel-mediated cellular toxicity

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12 December 2020

Inhibiting the conversion of soluble amyloid-beta peptide into abnormally folded amyloidogenic intermediates: relevance for Alzheimer's disease therapy.

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12 December 2020

Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives

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12 December 2020

Amyloid beta protein (1-40) forms calcium-permeable, Zn2+-sensitive channel in reconstituted lipid vesicles

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12 December 2020

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

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12 December 2020

Alzheimer's disease amyloid beta-protein forms Zn(2+)-sensitive, cation-selective channels across excised membrane patches from hypothalamic neurons

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12 December 2020

Prolines and amyloidogenicity in fragments of the Alzheimer's peptide beta/A4

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12 December 2020

Alzheimer's disease amyloid beta peptide 25-35 is localized in the membrane hydrocarbon core: x-ray diffraction analysis

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12 December 2020

Erratum: hirakura Y, lin M-C, kagan BL. 1999. Alzheimer amyloid Abeta1-42 channels: effects of solvent, pH, and congo red. J neurosci res 57:458-466

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12 December 2020

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

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12 December 2020

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

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12 December 2020

10.1007/S00232-003-0638-7

Identifiers

DOI

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6 December 2017

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