(Q44808678)

6 December 2017

title

Mechanisms of action of paracetamol and related analgesics (English)

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6 December 2017

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Garry G Graham

1

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6 December 2017

Kieran F Scott

series ordinal

2

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6 December 2017

publication date

1 January 2003

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6 December 2017

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6 December 2017

volume

11

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6 December 2017

issue

4

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6 December 2017

page(s)

401-413

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Perioperative pharmacodynamics of acetaminophen analgesia in children

6 December 2017

cites work

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https://api.crossref.org/works/10.1163%2F156856003322699573

Inhibition of prostaglandin H2 synthases by salicylate is dependent on the oxidative state of the enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Plasma and cerebrospinal fluid concentrations of paracetamol after a single intravenous dose of propacetamol

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H(2) synthases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Inhibition of arachidonic acid metabolism by antipyrine and 4-aminoantipyrine

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Paracetamol effectively reduces prostaglandin E2 synthesis in brain macrophages by inhibiting enzymatic activity of cyclooxygenase but not phospholipase and prostaglandin E synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Inflammatory molecule release by beta-amyloid-treated T98G astrocytoma cells: role of prostaglandins and modulation by paracetamol

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Antipyretic analgesics inhibit prostaglandin release from astrocytes and macrophages similarly

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Clinical pharmacokinetics of dipyrone and its metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Capsaicin-evoked prostaglandin E2 release in spinal cord slices: relative effect of cyclooxygenase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Mechanism of acetaminophen inhibition of cyclooxygenase isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors, using sensitive microsomal and platelet assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Effect of rofecoxib on nociception and the serotonin system in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Effects of acetaminophen on constitutive and inducible prostanoid biosynthesis in human blood cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Model representation of salicylate pharmacokinetics using unbound plasma salicylate concentrations and metabolite urinary excretion rates following a single oral dose.

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Induction of an acetaminophen-sensitive cyclooxygenase with reduced sensitivity to nonsteroid antiinflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

The enzymology of prostaglandin endoperoxide H synthases-1 and -2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Clinical patterns of hypersensitivity to nonsteroidal anti-inflammatory drugs and their pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Aspirin inhibits interleukin 1-induced prostaglandin H synthase expression in cultured endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Suppression of inducible cyclooxygenase 2 gene transcription by aspirin and sodium salicylate

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Cyclooxygenase-1 and Cyclooxygenase-2 Selectivity of Widely Used Nonsteroidal Anti-Inflammatory Drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1163%2F156856003322699573

Salicylates in rheumatoid arthritis: pharmacokinetics and analgesic response

21 January 2018

1 reference

12 December 2020

Effects of caffeine and paracetamol alone or in combination with acetylsalicylic acid on prostaglandin E(2) synthesis in rat microglial cells

1 reference

12 December 2020

Paracetamol does not potentiate the acetylsalicylate inhibition of prostaglandin release from macrophages

1 reference

12 December 2020

Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid

1 reference

12 December 2020

Endoscopic assessment of the effects of dipyrone (metamizol) in comparison to paracetamol and placebo on the gastric and duodenal mucosa of healthy adult volunteers

1 reference

12 December 2020

Paracetamol exerts a spinal antinociceptive effect involving an indirect interaction with 5-hydroxytryptamine3 receptors: in vivo and in vitro evidence

1 reference

12 December 2020

Sodium salicylate inhibits prostaglandin formation without affecting the induction of cyclooxygenase-2 by bacterial lipopolysaccharide in vivo

1 reference

12 December 2020

Biochemical and pharmacological effects of dipyrone and its metabolites in model systems related to arachidonic acid cascade

1 reference

12 December 2020

Current concepts of the actions of paracetamol (acetaminophen) and NSAIDs

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12 December 2020

Inhibition of anti-inflammatory drugs of prostaglandin production in cultured macrophages

1 reference

12 December 2020

10.1163/156856003322699573

Identifiers

DOI

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Dimensions Publication ID

6 December 2017

1015348846

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