(Q44837532)

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Quantitative imaging of neuroinflammation in human white matter: a positron emission tomography study with translocator protein 18 kDa radioligand, [18F]-FEPPA.

scientific article published on 28 July 2014

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scholarly article

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Europe PubMed Central

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10 March 2020

Quantitative imaging of neuroinflammation in human white matter: a positron emission tomography study with translocator protein 18 kDa radioligand, [18F]-FEPPA (English)

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10 March 2020

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positron emission tomography

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based on heuristic

inferred from title

3

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10 March 2020

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10 March 2020

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10 March 2020

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Ivonne Suridjan

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10 March 2020

Pablo M Rusjan

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10 March 2020

Nicolaas Paul L G Verhoeff

4

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10 March 2020

Aristotle N Voineskos

5

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10 March 2020

David Rotenberg

6

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10 March 2020

Alan A Wilson

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10 March 2020

Jeffrey H Meyer

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10 March 2020

publication date

28 July 2014

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10 March 2020

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10 March 2020

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10 March 2020

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10 March 2020

536-547

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10 March 2020

A new look at the statistical model identification

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Unified segmentation

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Translocator protein 18 kDa (TSPO): molecular sensor of brain injury and repair

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Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain

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PET visualization of microglia in multiple sclerosis patients using [11C]PK11195

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Proliferating resident microglia after focal cerebral ischaemia in mice

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Initial evaluation of 11C-DPA-713, a novel TSPO PET ligand, in humans

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“Mini-mental state”

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Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation

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Age and disease related changes in the translocator protein (TSPO) system in the human brain: positron emission tomography measurements with [11C]vinpocetine

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21 January 2018

Quantification of the specific translocator protein signal of 18F-PBR111 in healthy humans: a genetic polymorphism effect on in vivo binding.

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Microglia are the major cell type expressing MHC class II in human white matter

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Distinctive disruption patterns of white matter tracts in Alzheimer's disease with full diffusion tensor characterization

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Consensus nomenclature for in vivo imaging of reversibly binding radioligands

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21 January 2018

Cognitive processing speed in older adults: relationship with white matter integrity

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21 January 2018

Comparison of [(11)C]-(R)-PK 11195 and [(11)C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker

1 reference

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21 January 2018

A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation

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21 January 2018

Evaluation of age-related changes in translocator protein (TSPO) in human brain using (11)C-[R]-PK11195 PET.

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21 January 2018

Cerebral blood flow, blood volume and oxygen utilization. Normal values and effect of age.

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A strategy for removing the bias in the graphical analysis method

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21 January 2018

Myelin breakdown mediates age-related slowing in cognitive processing speed in healthy elderly men.

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The effects of aging, injury and disease on microglial function: a case for cellular senescence

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21 January 2018

Translocator protein (18 kDa) polymorphism (rs6971) explains in-vivo brain binding affinity of the PET radioligand [(18)F]-FEPPA.

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21 January 2018

Stereotaxic white matter atlas based on diffusion tensor imaging in an ICBM template

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21 January 2018

Translocator protein PET imaging for glial activation in multiple sclerosis

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21 January 2018

Microglial activation and dopamine terminal loss in early Parkinson's disease

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21 January 2018

Mixed-affinity binding in humans with 18-kDa translocator protein ligands

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21 January 2018

Two binding sites for [3H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammation

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21 January 2018

An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28

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21 January 2018

The effects of normal aging on myelin and nerve fibers: a review

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21 January 2018

An automated method for the extraction of regional data from PET images

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21 January 2018

Quantitation of translocator protein binding in human brain with the novel radioligand [18F]-FEPPA and positron emission tomography

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21 January 2018

Age-related alterations in white matter microstructure measured by diffusion tensor imaging.

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21 January 2018

A meta-analysis of diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease

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21 January 2018

Enlarged and phagocytic, but not primed, interleukin-1 alpha-immunoreactive microglia increase with age in normal human brain.

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Dystrophic microglia in the aging human brain

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Automated three-dimensional registration of magnetic resonance and positron emission tomography brain images by multiresolution optimization of voxel similarity measures.

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Selective age-related degradation of anterior callosal fiber bundles quantified in vivo with fiber tracking.

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Quantitative fiber tracking of lateral and interhemispheric white matter systems in normal aging: relations to timed performance

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21 January 2018

Neuroinflammation in healthy aging: a PET study using a novel Translocator Protein 18kDa (TSPO) radioligand, [(18)F]-FEPPA.

1 reference

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21 January 2018

The temporal dynamics of poststroke neuroinflammation: a longitudinal diffusion tensor imaging-guided PET study with 11C-PK11195 in acute subcortical stroke

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PK11195 labels activated microglia in Alzheimer's disease and in vivo in a mouse model using PET.

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The positron emission tomography ligand DAA1106 binds with high affinity to activated microglia in human neurological disorders

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Age-related decline in white matter tract integrity and cognitive performance: a DTI tractography and structural equation modeling study

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Radiosynthesis and initial evaluation of [18F]-FEPPA for PET imaging of peripheral benzodiazepine receptors

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21 January 2018

Increased binding of peripheral benzodiazepine receptor in Alzheimer's disease measured by positron emission tomography with [11C]DAA1106.

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Microglial activation in healthy aging

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Microglial activation in white matter lesions and nonlesional white matter of ageing brains

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Identifiers

10.1002/SYN.21765

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043159%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043159%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

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