(Q44869612)

7 December 2017

title

Pirfenidone inhibits NADPH-dependent microsomal lipid peroxidation and scavenges hydroxyl radicals (English)

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7 December 2017

H P Misra

1

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7 December 2017

C Rabideau

series ordinal

2

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7 December 2017

language of work or name

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1 January 2000

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Molecular and Cellular Biochemistry

7 December 2017

published in

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7 December 2017

volume

204

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7 December 2017

issue

1-2

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7 December 2017

page(s)

119-126

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Effect of the hydroxyl radical on fibroblast-mediated collagen remodelling in vitro

7 December 2017

cites work

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12 December 2020

Oxidative damage and fibrogenesis

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12 December 2020

Fibrogenic cytokines: the role of immune mediators in the development of scar tissue

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12 December 2020

Inhibition of tumor necrosis factor and subsequent endotoxin shock by pirfenidone

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12 December 2020

Effects of long-term oral beta-carotene supplementation on lipid peroxidation in patients with cystic fibrosis

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12 December 2020

Evidence for the involvement of the hydroxyl radical in the pathogenesis of excessive connective tissue proliferation in patients with tumor-endoprostheses

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12 December 2020

Increases in lung prolyl hydroxylase and superoxide dismutase activities during bleomycin-induced lung fibrosis in hamsters

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12 December 2020

Vitamin E dietary supplementation inhibits transforming growth factor beta 1 gene expression in the rat liver

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12 December 2020

Macrophage/fibroblast coculture induces macrophage inflammatory protein-1alpha production mediated by intercellular adhesion molecule-1 and oxygen radicals

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12 December 2020

Pirfenidone diminishes cyclophosphamide-induced lung fibrosis in mice

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12 December 2020

Pirfenidone reduces fibronectin synthesis by cultured human retinal pigment epithelial cells

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12 December 2020

Evidence that peroxidation of lysosomal membranes is initiated by hydroxyl free radicals produced during flavin enzyme activity

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12 December 2020

Spin trapping of superoxide and hydroxyl radicals with substituted pyrroline 1-oxides

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12 December 2020

Transport of iron and other transition metals into cells as revealed by a fluorescent probe

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12 December 2020

Preventive effect of pirfenidone against experimental sclerosing peritonitis in rats

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12 December 2020

On the mechanism of hydrogen peroxide-, superoxide-, and ultraviolet light-induced DNA cleavages of inactive bleomycin-iron(III) complex

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12 December 2020

The deoxyribose method: a simple "test-tube" assay for determination of rate constants for reactions of hydroxyl radicals

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12 December 2020

Direct measurement of free radical generation following reperfusion of ischemic myocardium

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12 December 2020

EPR kinetic studies of superoxide radicals generated during the autoxidation of 1-methyl-4-phenyl-2,3-dihydropyridinium, a bioactivated intermediate of parkinsonian-inducing neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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12 December 2020

Activation of the second promoter of the transforming growth factor-beta 1 gene by transforming growth factor-beta 1 and phorbol ester occurs through the same target sequences

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12 December 2020

Possible mechanism of chrysotile asbestos-stimulated superoxide anion production in guinea pig alveolar macrophages

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12 December 2020

Acute pneumocyte injury, poly(ADP-ribose) polymerase activity, and pyridine nucleotide levels after in vitro exposure of murine lung slices to cyclophosphamide

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12 December 2020

Pirfenidone induces intercellular adhesion molecule-1 (ICAM-1) down-regulation on cultured human synovial fibroblasts

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12 December 2020

Ascorbic acid and collagen synthesis: rethinking a role for lipid peroxidation

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12 December 2020

Hepatic microsomal ethanol oxidation. Hydrogen peroxide formation and the role of catalase

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12 December 2020

Malondialdehyde stimulates collagen production by hepatic lipocytes only upon activation in primary culture.

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12 December 2020

EPR studies of spin-trapped free radicals in paraquat-treated lung microsomes

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12 December 2020

The Role of Superoxide Anion in the Autoxidation of Epinephrine and a Simple Assay for Superoxide Dismutase

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12 December 2020

Lung fibrosis is ameliorated by pirfenidone fed in diet after the second dose in a three-dose bleomycin-hamster model

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12 December 2020

Reduction of oxidative stress by oral N-acetyl-L-cysteine treatment decreases plasma soluble vascular cell adhesion molecule-1 concentrations in non-obese, non-dyslipidaemic, normotensive, patients with non-insulin-dependent diabetes

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12 December 2020

The generation of hydroxyl radicals in biologic systems: toxicological aspects

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12 December 2020

Vitamin E dietary supplementation protects against carbon tetrachloride-induced chronic liver damage and cirrhosis

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12 December 2020

The reduction of cytochrome c by milk xanthine oxidase

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12 December 2020

Tumor necrosis factor alpha functions in an autocrine manner in the induction of human immunodeficiency virus expression

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12 December 2020

Mechanisms of bleomycin-induced lung damage

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12 December 2020

Prevention of CCL4-induced liver cirrhosis by silymarin

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12 December 2020

Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)

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12 December 2020

Formation of superoxide and hydroxy radicals in iron(II)-bleomycin-oxygen system: Electron spin resonance detection by spin trapping

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12 December 2020

The role of free radicals in asbestos-induced diseases

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12 December 2020

The role of free radicals in the pathogenesis of amiodarone toxicity

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12 December 2020

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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12 December 2020

Pirfenidone: a novel pharmacological agent that inhibits leiomyoma cell proliferation and collagen production

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12 December 2020

Dietary intake of pirfenidone ameliorates bleomycin-induced lung fibrosis in hamsters

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12 December 2020

The reaction between thiobarbituric acid and the oxidation products of certain lipides

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12 December 2020

Antiarrhythmic agents. Scavengers of hydroxyl radicals and inhibitors of NADPH-dependent lipid peroxidation in bovine lung microsomes

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12 December 2020

The role of superoxide and singlet oxygen in lipid peroxidation

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12 December 2020

Protective Effects of Human Recombinant Mnsod in Adjuvant Arthritis and Bleomycin-Induced Lung Fibrosis

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12 December 2020

Identifiers

DOI

10.1023/A:1007023532508

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Dimensions Publication ID

7 December 2017

1043013992

0 references

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