(Q44878263)

English

Adenovirus encoding human platelet-derived growth factor-B delivered in collagen exhibits safety, biodistribution, and immunogenicity profiles favorable for clinical use.

scientific article published in May 2004

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scholarly article

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Europe PubMed Central

7 December 2017

Adenovirus encoding human platelet-derived growth factor-B delivered in collagen exhibits safety, biodistribution, and immunogenicity profiles favorable for clinical use. (English)

1 reference

Europe PubMed Central

7 December 2017

1 reference

based on heuristic

inferred from title

author name string

Dan-ling Gu

1

1 reference

Europe PubMed Central

7 December 2017

Thanh Nguyen

2

1 reference

Europe PubMed Central

7 December 2017

Ana Maria Gonzalez

3

1 reference

Europe PubMed Central

7 December 2017

Marie A Printz

4

1 reference

Europe PubMed Central

7 December 2017

Glenn F Pierce

5

1 reference

Europe PubMed Central

7 December 2017

Barbara A Sosnowski

6

1 reference

Europe PubMed Central

7 December 2017

M Laurie Phillips

7

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Europe PubMed Central

7 December 2017

Lois A Chandler

8

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Europe PubMed Central

7 December 2017

publication date

1 May 2004

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Europe PubMed Central

7 December 2017

Molecular Therapy

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Europe PubMed Central

7 December 2017

9

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Europe PubMed Central

7 December 2017

5

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Europe PubMed Central

7 December 2017

699-711

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Europe PubMed Central

7 December 2017

Detection of platelet-derived growth factor (PDGF)-AA in actively healing human wounds treated with recombinant PDGF-BB and absence of PDGF in chronic nonhealing wounds

1 reference

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Efficacy and safety of becaplermin (recombinant human platelet-derived growth factor-BB) in patients with nonhealing, lower extremity diabetic ulcers: a combined analysis of four randomized studies

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7 January 2021

Pharmacologic enhancement of wound healing

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The role of growth factors in wound healing

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Therapeutic application of growth factors

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Role of hypoxia in growth factor responses: differential effects of basic fibroblast growth factor and platelet-derived growth factor in an ischemic wound model

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Efficacy and safety of a topical gel formulation of recombinant human platelet-derived growth factor-BB (becaplermin) in patients with chronic neuropathic diabetic ulcers. A phase III randomized placebo-controlled double-blind study

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Clinical efficacy of becaplermin (rhPDGF-BB) gel. Becaplermin Gel Studies Group

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Virus-mediated gene transfer for cutaneous gene therapy

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Adenoviral-mediated gene transfer in wound healing

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Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma.

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Impact of preexisting and induced humoral and cellular immune responses in an adenovirus-based gene therapy phase I clinical trial for localized mesothelioma.

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Stimulation of new bone formation by direct transfer of osteogenic plasmid genes

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Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration

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Matrix-enabled gene transfer for cutaneous wound repair

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De novo generation of permanent neovascularized soft tissue appendages by platelet-derived growth factor

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Angiotensin II improves random-flap viability in a rat model

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Effects of a collagen matrix containing basic fibroblast growth factor on wound contraction

1 reference

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FGF2-Targeted adenovirus encoding platelet-derived growth factor-B enhances de novo tissue formation

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Matrix immobilization enhances the tissue repair activity of growth factor gene therapy vectors

1 reference

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Type I, II, III, IV, V, and VI collagens serve as extracellular ligands for the isoforms of platelet-derived growth factor (AA, BB, and AB)

1 reference

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Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

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Therapeutic Effects of Dehydroepiandrosterone (DHEA) in Diabetic Mice

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Mechanism of action and in vivo role of platelet-derived growth factor

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Recombinant adenoviral mediated gene transfer in ischemic impaired wound healing

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Adenoviral-mediated gene transfer in wound healing: acute inflammatory response in human skin in the SCID mouse model

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Fibroblast growth factor 2-retargeted adenoviral vectors exhibit a modified biolocalization pattern and display reduced toxicity relative to native adenoviral vectors

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Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administration

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Macrophage depletion increases the safety, efficacy and persistence of adenovirus-mediated gene transfer in vivo

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Adenovirus-mediated in vivo gene transfer

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High efficiency genetic modification of hair follicles and growing hair shafts

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Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses

1 reference

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10.1016/J.YMTHE.2004.02.018

1 reference

Europe PubMed Central

7 December 2017

1 reference

Europe PubMed Central

7 December 2017

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