(Q44894508)

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Targeted deletion of the kynurenine aminotransferase ii gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via alpha7 nicotinic receptors in the hippocampus.

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Europe PubMed Central

7 December 2017

Targeted deletion of the kynurenine aminotransferase ii gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via alpha7 nicotinic receptors in the hippocampus (English)

1 reference

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12 May 2020

author name string

Manickavasagon Alkondon

1

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12 May 2020

Edna F R Pereira

2

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12 May 2020

Ping Yu

3

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12 May 2020

Emerson Z Arruda

4

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12 May 2020

Luis E F Almeida

5

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12 May 2020

Paolo Guidetti

6

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12 May 2020

William P Fawcett

7

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12 May 2020

Michael T Sapko

8

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12 May 2020

William R Randall

9

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12 May 2020

Robert Schwarcz

10

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12 May 2020

Danilo A Tagle

11

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12 May 2020

Edson X Albuquerque

12

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12 May 2020

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publication date

1 May 2004

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Europe PubMed Central

7 December 2017

Journal of Neuroscience

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12 May 2020

24

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12 May 2020

4635-4648

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12 May 2020

19

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12 May 2020

Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kynurenine metabolism in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distributions of nicotinic acetylcholine receptor alpha7 and beta2 subunits on cultured hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic mice expressing mutated full-length HD cDNA: a paradigm for locomotor changes and selective neuronal loss in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic organization and expression analysis of mouse kynurenine aminotransferase II, a possible factor in the pathophysiology of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal nicotinic receptors in dementia with Lewy bodies and schizophrenia: alpha-bungarotoxin and nicotine binding in the thalamus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative differences in the effects of de novo produced and exogenous kynurenic acid in rat brain slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of NMDA-receptor antagonists on long-term potentiation and hypoxic/hypoglycaemic excitotoxicity in hippocampal slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel hippocampal interneuronal subtypes identified using transgenic mice that express green fluorescent protein in GABAergic interneurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On neurodegenerative diseases, models, and treatment strategies: lessons learned and lessons forgotten a generation following the cholinergic hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D-amino acids as putative neurotransmitters: focus on D-serine

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterisation of kynurenine pathway metabolism in human astrocytes and implications in neuropathogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kynurenine 3-hydroxylase inhibition in rats: effects on extracellular kynurenic acid concentration and N-methyl-D-aspartate-induced depolarisation in the striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kynurenic acid antagonists and kynurenine pathway inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of mecamylamine stereoisomers on human nicotinic receptor subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuron-astrocyte cross-talk during synaptic transmission: physiological and neuropathological implications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased cortical kynurenate content in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic acetylcholine receptor alpha7 and alpha4beta2 subtypes differentially control GABAergic input to CA1 neurons in rat hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo monitoring of amino acids by direct sampling of brain extracellular fluid at ultralow flow rates and capillary electrophoresis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A non-alpha7 nicotinic acetylcholine receptor modulates excitatory input to hippocampal CA1 interneurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic receptors and hippocampal synaptic plasticity ... it's all in the timing

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unconventional ligands and modulators of nicotinic receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of the alpha7 nicotinic cholinergic receptor in rat hippocampal formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hippocampal network patterns of activity in the mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kynurenate production by cultured human astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA and AMPA Receptors Contribute to the Nicotinic Cholinergic Excitation of CA1 Interneurons in the Rat Hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABAergic systems modulate nicotinic receptor-mediated seizures in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glycine transporter type 1 inhibitor N-[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in rodent behavior.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel neural modulators

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional mapping and Ca2+ regulation of nicotinic acetylcholine receptor channels in rat hippocampal CA1 neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse strain-specific nicotinic acetylcholine receptor expression by inhibitory interneurons and astrocytes in the dorsal hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunocytochemical localization of kynurenine aminotransferase in the rat striatum: a light and electron microscopic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competitive antagonists and partial agonists at the glycine modulatory site of the mouse N-methyl-D-aspartate receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral effects of GABA in the hippocampal formation: functional interaction with histamine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine enhances NMDA-receptor mediated synaptic potentials in neocortical slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of NMDA receptor-mediated responses by glycine and D-serine in the rat thalamus in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sites of antagonist action on N-methyl-D-aspartic acid receptors studied using fluctuation analysis and a rapid perfusion technique.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence of Kynurenic Acid in the Mammalian Brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and quantification of kynurenic acid in human brain tissue.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Genetically Controlled Hippocampal Transmitter System Regulating Exploratory Behavior in Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-acetylaspartylglutamate inhibits forskolin-stimulated cyclic AMP levels via a metabotropic glutamate receptor in cultured cerebellar granule cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitatory synaptic connections onto rat hippocampal inhibitory cells may involve a single transmitter release site.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pentafluorobenzylation method for quantification of acidic tryptophan metabolites using electron capture negative ion mass spectrometry.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-Aminoadipate-2-oxoglutarate aminotransferase isoenzymes in human liver: a plausible physiological role in lysine and tryptophan metabolism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropharmacology of quinolinic and kynurenic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ST/b and DBA/2 mice differ in brain alpha-bungarotoxin binding and alpha 7 nicotinic receptor subunit mRNA levels: a quantitative autoradiographic analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyramidal cell dendrites are the primary targets of calbindin D28k-immunoreactive interneurons in the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Properties of neuronal nicotinic acetylcholine receptors: pharmacological characterization and modulation of synaptic function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nagging question of the function of N-acetylaspartylglutamate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of rat brain kynurenine aminotransferases I and II.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel systemically active antagonists of the glycine site of the N-methyl-D-aspartate receptor: electrophysiological, biochemical and behavioral characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schizophrenia and glutamatergic transmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine and N-methyl-D-aspartate receptors: physiological significance and possible therapeutic applications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of N-methyl-D-aspartate receptor function by glycine transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/15140935

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.5631-03.2004

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729395&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729395&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729395&resulttype=core&format=json

12 May 2020

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