(Q44933756)

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Depleting regulatory T cells with arginine-rich, cell-penetrating, peptide-conjugated morpholino oligomer targeting FOXP3 inhibits regulatory T-cell function.

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14 February 2020

Depleting regulatory T cells with arginine-rich, cell-penetrating, peptide-conjugated morpholino oligomer targeting FOXP3 inhibits regulatory T-cell function (English)

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14 February 2020

Herbert Kim Lyerly

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14 February 2020

Patrick L Iversen

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14 February 2020

author name string

M A Morse

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14 February 2020

A Hobeika

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14 February 2020

D Serra

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14 February 2020

K Aird

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14 February 2020

M McKinney

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14 February 2020

A Aldrich

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14 February 2020

T Clay

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14 February 2020

D Mourich

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G R Devi

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14 February 2020

publication date

14 October 2011

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14 February 2020

Cancer Gene Therapy

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14 February 2020

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14 February 2020

1

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14 February 2020

30-37

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14 February 2020

https://scigraph.springernature.com/pub.10.1038/cgt.2011.63

0 references

FOXP3+ regulatory T cells in the human immune system

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Naturally-occurring CD4+CD25+ immunoregulatory T cells: central players in the arena of peripheral tolerance

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Immunoregulatory T cells in tumor immunity

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Escape from immunotherapy: possible mechanisms that influence tumor regression/progression.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Regulatory T cells and breast cancer: implications for immunopathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

In vivo elimination of CD25+ regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8+ T cells and reduces chronic retroviral set points

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

IL-2 immunotoxin therapy modulates tumor-associated regulatory T cells and leads to lasting immune-mediated rejection of breast cancers in neu-transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

IL-2 immunotoxin denileukin diftitox reduces regulatory T cells and enhances vaccine-mediated T-cell immunity

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Functional analysis of FOXP3.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Control of regulatory T cell development by the transcription factor Foxp3

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

A peptide inhibitor of FOXP3 impairs regulatory T cell activity and improves vaccine efficacy in mice.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Morpholino antisense oligomers: design, preparation, and properties

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Neutrally charged phosphorodiamidate morpholino antisense oligomers: uptake, efficacy and pharmacokinetics.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Targeting platelet-leukocyte interactions: identification of the integrin Mac-1 binding site for the platelet counter receptor glycoprotein Ibalpha

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Cutting edge: induction of B7-H4 on APCs through IL-10: novel suppressive mode for regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Antisense targeting of cFLIP sensitizes activated T cells to undergo apoptosis and desensitizes responses to contact dermatitis.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Morpholinos and their peptide conjugates: therapeutic promise and challenge for Duchenne muscular dystrophy

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

The main function of IL-2 is to promote the development of T regulatory cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

In vivo bioavailability and pharmacokinetics of a c-MYC antisense phosphorodiamidate morpholino oligomer, AVI-4126, in solid tumors

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Cellular uptake of neutral phosphorodiamidate morpholino oligomers.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Delivery of phosphorodiamidate morpholino antisense oligomers in cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Pharmacokinetics, biodistribution, stability and toxicity of a cell-penetrating peptide-morpholino oligomer conjugate.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Antisense phosphorodiamidate morpholino oligomers targeted to an essential gene inhibit Burkholderia cepacia complex.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Arginine-rich cell-penetrating peptides facilitate delivery of antisense oligomers into murine leukocytes and alter pre-mRNA splicing

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

21 January 2018

Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

7 January 2021

based on heuristic

inferred from DOI database lookup

Depletion of CD4+CD25+ human regulatory T cells in vivo: kinetics of Treg depletion and alterations in immune functions in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.63

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/CGT.2011.63

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21997230%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21997230%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

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