(Q44939687)

7 December 2017

title

Structure--activity relationships of hainantoxin-IV and structure determination of active and inactive sodium channel blockers (English)

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7 December 2017

Dongling Li

1

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7 December 2017

Yucheng Xiao

2

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7 December 2017

Xia Xu

3

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7 December 2017

Xia Xiong

4

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7 December 2017

Shanyun Lu

5

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7 December 2017

Zhonghua Liu

6

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7 December 2017

Qi Zhu

7

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7 December 2017

Meichi Wang

8

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7 December 2017

Xiaocheng Gu

9

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7 December 2017

Songping Liang

10

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7 December 2017

language of work or name

English

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publication date

16 June 2004

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Journal of Biological Chemistry

7 December 2017

published in

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7 December 2017

volume

279

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7 December 2017

issue

36

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7 December 2017

page(s)

37734-37740

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A quantitative description of membrane current and its application to conduction and excitation in nerve

7 December 2017

cites work

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From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels

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Molecular mechanisms of neurotoxin action on voltage-gated sodium channels.

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21 January 2018

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Isolation and characterization of hainantoxin-IV, a novel antagonist of tetrodotoxin-sensitive sodium channels from the Chinese bird spider Selenocosmia hainana

21 January 2018

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Function and solution structure of huwentoxin-IV, a potent neuronal tetrodotoxin (TTX)-sensitive sodium channel antagonist from Chinese bird spider Selenocosmia huwena

21 January 2018

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Purification and characterization of Hainantoxin-V, a tetrodotoxin-sensitive sodium channel inhibitor from the venom of the spider Selenocosmia hainana

21 January 2018

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Function and solution structure of hainantoxin-I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana

21 January 2018

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Role of disulfide bonds in folding and activity of leiurotoxin I: just two disulfides suffice

21 January 2018

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The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy

21 January 2018

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21 January 2018

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A common structural motif incorporating a cystine knot and a triple-stranded beta-sheet in toxic and inhibitory polypeptides

21 January 2018

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Relationship between nuclear magnetic resonance chemical shift and protein secondary structure

21 January 2018

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Structure-activity relationships of mu-conotoxin GIIIA: structure determination of active and inactive sodium channel blocker peptides by NMR and simulated annealing calculations

21 January 2018

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Action of derivatives of mu-conotoxin GIIIA on sodium channels. Single amino acid substitutions in the toxin separately affect association and dissociation rates

21 January 2018

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Modification of Arg-13 of mu-conotoxin GIIIA with piperidinyl-Arg analogs and their relation to the inhibition of sodium channels

21 January 2018

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Charge conversion enables quantification of the proximity between a normally-neutral mu-conotoxin (GIIIA) site and the Na+ channel pore

21 January 2018

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Electrostatic and steric contributions to block of the skeletal muscle sodium channel by mu-conotoxin

21 January 2018

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Novel structural determinants of mu-conotoxin (GIIIB) block in rat skeletal muscle (mu1) Na+ channels

21 January 2018

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Clockwise domain arrangement of the sodium channel revealed by (mu)-conotoxin (GIIIA) docking orientation.

21 January 2018

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Discrimination of muscle and neuronal Na-channel subtypes by binding competition between [3H]saxitoxin and mu-conotoxins

21 January 2018

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Pore residues critical for mu-CTX binding to rat skeletal muscle Na+ channels revealed by cysteine mutagenesis

21 January 2018

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Three-dimensional solution structure of mu-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels

21 January 2018

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Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels

21 January 2018

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Solution structure of the sodium channel antagonist conotoxin GS: a new molecular caliper for probing sodium channel geometry

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M405765200

1 reference

7 December 2017

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