(Q44958675)

English

Soluble, oligomeric, and ligand-binding extracellular domain of the human alpha7 acetylcholine receptor expressed in yeast: replacement of the hydrophobic cysteine loop by the hydrophilic loop of the ACh-binding protein enhances protein solubility

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scholarly article

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Europe PubMed Central

PubMed publication ID

7 December 2017

Soluble, oligomeric, and ligand-binding extracellular domain of the human alpha7 acetylcholine receptor expressed in yeast: replacement of the hydrophobic cysteine loop by the hydrophilic loop of the ACh-binding protein enhances protein solubility (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

1 reference

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author name string

Vassiliki Avramopoulou

1

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Avgi Mamalaki

2

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Socrates J Tzartos

3

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

language of work or name

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publication date

29 June 2004

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Europe PubMed Central

PubMed publication ID

7 December 2017

number of pages

7

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inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

7 December 2017

279

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Europe PubMed Central

PubMed publication ID

7 December 2017

37

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

38287-38293

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Evolutionary history of the ligand-gated ion-channel superfamily of receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

The diversity of neuronal nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Neuronal nicotinic receptors, important new players in brain function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Presynaptic nicotinic ACh receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Human neuronal nicotinic receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Nicotinic acetylcholine receptors in health and disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Nicotinic acetylcholine receptor at 4.6 A resolution: transverse tunnels in the channel wall.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the alpha subunits.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Rapid preparation of the nicotinic acetylcholine receptor for crystallization in detergent solution.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Electron microscopic evidence for nucleation and growth of 3D acetylcholine receptor microcrystals in structured lipid-detergent matrices

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Improved secondary structure predictions for a nicotinic receptor subunit: incorporation of solvent accessibility and experimental data into a two-dimensional representation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Topology of ligand binding sites on the nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

The nicotinic receptor ligand binding domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Water-soluble nicotinic acetylcholine receptor formed by alpha7 subunit extracellular domains.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

A method for soluble overexpression of the alpha7 nicotinic acetylcholine receptor extracellular domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

"Weak toxin" from Naja kaouthia is a nontoxic antagonist of alpha 7 and muscle-type nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Heterologous protein expression in the methylotrophic yeast Pichia pastoris

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Recombinant protein expression in Pichia pastoris

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Expression of soluble ligand- and antibody-binding extracellular domain of human muscle acetylcholine receptor alpha subunit in yeast Pichia pastoris. Role of glycosylation in alpha-bungarotoxin binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Electron microscopic evidence for the assembly of soluble pentameric extracellular domains of the nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Three-dimensional structure of the acetylcholine receptor by cryoelectron microscopy and helical image reconstruction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Mutational analysis of roles for extracellular cysteine residues in the assembly and function of human alpha 7-nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Expression and spectroscopic analysis of soluble nicotinic acetylcholine receptor fragments derived from the extracellular domain of the alpha-subunit.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Identification of regions involved in the binding of alpha-bungarotoxin to the human alpha7 neuronal nicotinic acetylcholine receptor using synthetic peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Reconstitution of conformationally dependent epitopes on the N-terminal extracellular domain of the human muscle acetylcholine receptor alpha subunit expressed in Escherichia coli: implications for myasthenia gravis therapeutic approaches

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

N-glycosylation at the conserved sites ensures the expression of properly folded functional ACh receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402533200

21 January 2018

Identifiers

10.1074/JBC.M402533200

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

ResearchGate publication ID

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