(Q44960327)

7 December 2017

title

Homo-oligomerization is the essential function of the tandem BRCT domains in the checkpoint protein Crb2. (English)

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7 December 2017

1

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7 December 2017

Bettina A Moser

2

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7 December 2017

Paul Russell

series ordinal

3

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7 December 2017

language of work or name

English

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publication date

30 June 2004

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Journal of Biological Chemistry

7 December 2017

published in

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7 December 2017

volume

279

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7 December 2017

issue

37

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7 December 2017

page(s)

38409-38414

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BRCA1 protein products ... Functional motifs...

7 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403326200

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Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor

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Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure

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BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

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The BRCT Domain Is a Phospho-Protein Binding Domain

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Conserved BRCT regions of TopBP1 and of the tumor suppressor BRCA1 bind strand breaks and termini of DNA

21 January 2018

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Isolation and characterization of the Schizosaccharomyces pombe rhp9 gene: a gene required for the DNA damage checkpoint but not the replication checkpoint

21 January 2018

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Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.

21 January 2018

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Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1

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53BP1, a mediator of the DNA damage checkpoint

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Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

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p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

21 January 2018

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Retention but not recruitment of Crb2 at double-strand breaks requires Rad1 and Rad3 complexes.

21 January 2018

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Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast

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Regulation of checkpoint kinases through dynamic interaction with Crb2.

21 January 2018

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Ste5 RING-H2 domain: role in Ste4-promoted oligomerization for yeast pheromone signaling

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21 January 2018

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Hus1p, a conserved fission yeast checkpoint protein, interacts with Rad1p and is phosphorylated in response to DNA damage

21 January 2018

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Detection of protein folding defects caused by BRCA1-BRCT truncation and missense mutations

21 January 2018

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Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint

21 January 2018

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Budding yeast Rad9 is an ATP-dependent Rad53 activating machine.

21 January 2018

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Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast

21 January 2018

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Phosphorylation activates Chk1 and is required for checkpoint-mediated cell cycle arrest

21 January 2018

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The cancer-predisposing mutation C61G disrupts homodimer formation in the NH2-terminal BRCA1 RING finger domain

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M403326200

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7 December 2017

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