(Q44962410)

21228172

7 December 2017

title

PKC ε activation prevents synaptic loss, Aβ elevation, and cognitive deficits in Alzheimer's disease transgenic mice (English)

1 reference

7 December 2017

1 reference

Jarin Hongpaisan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6623433&resulttype=core&format=json

15 May 2020

Miao-Kun Sun

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6623433&resulttype=core&format=json

15 May 2020

Daniel L Alkon

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6623433&resulttype=core&format=json

15 May 2020

language of work or name

English

0 references

publication date

1 January 2011

1 reference

21228172

7 December 2017

number of pages

14

1 reference

inferred from page(s)

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6623433&resulttype=core&format=json

15 May 2020

volume

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6623433&resulttype=core&format=json

15 May 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6623433&resulttype=core&format=json

15 May 2020

page(s)

630-643

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6623433&resulttype=core&format=json

describes a project that uses

15 May 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6623433/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

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Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype

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12 December 2020

Differential regulation of glycogen synthase kinase-3 beta by protein kinase C isotypes

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12 December 2020

PKC signaling mediates global enhancement of excitatory synaptogenesis in neurons triggered by local contact with astrocytes

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12 December 2020

Regulation of protein kinase C by the anti-Parkinson drug, MAO-B inhibitor, rasagiline and its derivatives, in vivo

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12 December 2020

Amyloid beta peptide directly inhibits PKC activation

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12 December 2020

Dendritic spines disappear with chilling but proliferate excessively upon rewarming of mature hippocampus.

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Morphological characterization of Thioflavin-S-positive amyloid plaques in transgenic Alzheimer mice and effect of passive Abeta immunotherapy on their clearance

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Neuronal ELAV proteins enhance mRNA stability by a PKCalpha-dependent pathway

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Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1.

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12 December 2020

The linoleic acid derivative DCP-LA selectively activates PKC-epsilon, possibly binding to the phosphatidylserine binding site

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12 December 2020

Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease

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12 December 2020

PKCepsilon increases endothelin converting enzyme activity and reduces amyloid plaque pathology in transgenic mice.

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12 December 2020

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12 December 2020

Activation of protein kinase C modulates BACE1-mediated beta-secretase activity

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12 December 2020

ADAM-10 over-expression increases cortical synaptogenesis

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12 December 2020

Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

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12 December 2020

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Poststroke neuronal rescue and synaptogenesis mediated in vivo by protein kinase C in adult brains

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12 December 2020

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12 December 2020

Neuroprotective versus tumorigenic protein kinase C activators

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12 December 2020

Mitochondrial trafficking of APP and alpha synuclein: Relevance to mitochondrial dysfunction in Alzheimer's and Parkinson's diseases

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12 December 2020

Postischemic PKC activation rescues retrograde and anterograde long-term memory

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12 December 2020

Promising multifunctional anti-Alzheimer's dimer bis(7)-Cognitin acting as an activator of protein kinase C regulates activities of alpha-secretase and BACE-1 concurrently

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12 December 2020

Reduction of beta-amyloid levels by novel protein kinase C(epsilon) activators

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Synapse Loss and Gliosis in the Molecular Layer of the Cerebral Cortex in Alzheimer's Disease and in Frontal Lobe Degeneration

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Glycogen synthase kinase 3β is identical to tau protein kinase I generating several epitopes of paired helical filaments

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Ca2+-dependent and Ca2+-independent protein kinase C changes in the brain of patients with Alzheimer's disease

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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12 December 2020

Administration of corticosterone alters intracellular localization of brain-derived neurotrophic factor-like immunoreactivity in the rat brain.

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12 December 2020

Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease.

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12 December 2020

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Protein kinase C expression and activity after global incomplete cerebral ischemia in dogs

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12 December 2020

10.1523/JNEUROSCI.5209-10.2011

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6623433&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6623433&resulttype=core&format=json

15 May 2020

21228172

1 reference