(Q44963738)

7 December 2017

title

ADAM10 overexpression shifts lympho- and myelopoiesis by dysregulating site 2/site 3 cleavage products of Notch (English)

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7 December 2017

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David R Gibb

1

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7 December 2017

Sheinei J Saleem

2

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7 December 2017

Dae-Joong Kang

3

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7 December 2017

Mark A Subler

4

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7 December 2017

Daniel H Conrad

5

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7 December 2017

language of work or name

English

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publication date

2 March 2011

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7 December 2017

published in

Journal of Immunology

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7 December 2017

volume

186

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7 December 2017

issue

7

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7 December 2017

page(s)

4244-4252

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A new paradigm for hematopoietic cell lineages: revision of the classical concept of the myeloid-lymphoid dichotomy

7 December 2017

cites work

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12 December 2020

Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations

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12 December 2020

Bipotential B-macrophage progenitors are present in adult bone marrow.

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12 December 2020

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

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12 December 2020

Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.

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12 December 2020

Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development

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12 December 2020

Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage

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12 December 2020

Notch signaling induces multilineage myeloid differentiation and up-regulates PU.1 expression.

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12 December 2020

Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development

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12 December 2020

Bone-marrow haematopoietic-stem-cell niches

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12 December 2020

T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice.

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12 December 2020

Malignant transformation of early lymphoid progenitors in mice expressing an activated Blk tyrosine kinase

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12 December 2020

Lineage specification and plasticity in CD19- early B cell precursors

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12 December 2020

ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23

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12 December 2020

The earliest thymic progenitors for T cells possess myeloid lineage potential.

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12 December 2020

Inhibition of KSHV-infected primary effusion lymphomas in NOD/SCID mice by gamma-secretase inhibitor.

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12 December 2020

Notch signaling controls the generation and differentiation of early T lineage progenitors

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12 December 2020

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

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12 December 2020

A B220+ CD117+ CD19- hematopoietic progenitor with potent lymphoid and myeloid developmental potential

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12 December 2020

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity

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12 December 2020

T-cell potential and development in vitro: the OP9-DL1 approach

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12 December 2020

Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

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12 December 2020

Adult T-cell progenitors retain myeloid potential

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12 December 2020

Notch1 perturbation of hemopoiesis involves non-cell- autonomous modifications

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12 December 2020

The canonical Notch signaling pathway: unfolding the activation mechanism

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12 December 2020

Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome

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12 December 2020

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

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12 December 2020

The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex

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12 December 2020

Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling

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12 December 2020

Notch signaling in the immune system

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12 December 2020

Untangling the T branch of the hematopoiesis tree

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12 December 2020

Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia

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12 December 2020

ADAMs: key components in EGFR signalling and development

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12 December 2020

Myeloid-derived suppressor cells: linking inflammation and cancer

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12 December 2020

ADAM10 is essential for proteolytic activation of Notch during thymocyte development.

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12 December 2020

Metalloprotease ADAM10 is required for Notch1 site 2 cleavage.

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12 December 2020

ADAM10 as a therapeutic target for cancer and inflammation

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12 December 2020

Biological and molecular evidence for existence of lymphoid-primed multipotent progenitors

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12 December 2020

ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo

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12 December 2020

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

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12 December 2020

Humoral response suppression observed with CD23 transgenics.

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12 December 2020

Notch in lymphopoiesis and T cell polarization

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12 December 2020

Regulation of lymphocyte development by Notch signaling

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12 December 2020

Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines

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12 December 2020

Notch signalling via RBP-J promotes myeloid differentiation.

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12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1003318

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7 December 2017

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