(Q44997634)

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Crystal structure and mutagenesis of a protein phosphatase-1:calcineurin hybrid elucidate the role of the beta12-beta13 loop in inhibitor binding

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Europe PubMed Central

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8 December 2017

Crystal structure and mutagenesis of a protein phosphatase-1:calcineurin hybrid elucidate the role of the beta12-beta13 loop in inhibitor binding (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

protein structure

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crystal structure

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based on heuristic

inferred from title

author name string

Jason T Maynes

1

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Europe PubMed Central

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8 December 2017

Kathleen R Perreault

2

1 reference

Europe PubMed Central

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8 December 2017

Maia M Cherney

3

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Europe PubMed Central

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8 December 2017

Hue Anh Luu

4

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Europe PubMed Central

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8 December 2017

Michael N G James

5

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8 December 2017

Charles F B Holmes

6

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8 December 2017

language of work or name

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publication date

26 July 2004

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8 December 2017

Journal of Biological Chemistry

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8 December 2017

279

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8 December 2017

41

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Europe PubMed Central

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8 December 2017

43198-43206

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

The discovery of protein phosphatases: from chaos and confusion to an understanding of their role in cell regulation and human disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Inhibition of the Ser-Thr phosphatases PP1 and PP2A by naturally occurring toxins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Molecular mechanisms underlying inhibition of protein phosphatases by marine toxins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Inhibitors of protein kinases and phosphatases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Protein phosphatase 1 regulation by inhibitors and targeting subunits

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Interaction of inhibitor-2 with the catalytic subunit of type 1 protein phosphatase. Identification of a sequence analogous to the consensus type 1 protein phosphatase-binding motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Characterization of the PP2A alpha gene mutation in okadaic acid-resistant variants of CHO-K1 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Mutagenesis of the L7 loop connecting beta strands 12 and 13 of calcineurin: evidence for a structural role in activity changes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Crystal structure of the catalytic subunit of human protein phosphatase 1 and its complex with tungstate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Crystal structure of the complex between calyculin A and the catalytic subunit of protein phosphatase 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Molecular enzymology underlying regulation of protein phosphatase-1 by natural toxins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Inhibitor-2 functions like a chaperone to fold three expressed isoforms of mammalian protein phosphatase-1 into a conformation with the specificity and regulatory properties of the native enzyme.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Main-chain bond lengths and bond angles in protein structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Dictyostelium discoideum protein phosphatase-1 catalytic subunit exhibits distinct biochemical properties.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Identification by molecular cloning of two cDNA sequences from the plant Brassica napus which are very similar to mammalian protein phosphatases-1 and -2A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Molecular cloning and chromosomal mapping of type one serine/threonine protein phosphatases in Arabidopsis thaliana

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Molecular cloning of the cDNA encoding a stress-inducible protein phosphatase 1 (PP1) catalytic subunit from French bean (Phaseolus vulgaris L.)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Identification of high levels of type 1 and type 2A protein phosphatases in higher plants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Structural basis of protein phosphatase 1 regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Importance of the β12-β13 Loop in Protein Phosphatase-1 Catalytic Subunit for Inhibition by Toxins and Mammalian Protein Inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M407184200

21 January 2018

Identifiers

10.1074/JBC.M407184200

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 December 2017

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