(Q45004321)

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Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons

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scholarly article

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Europe PubMed Central

8 December 2017

Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons (English)

1 reference

Europe PubMed Central

8 December 2017

apoptotic process

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1 reference

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author name string

Kanai H

1

1 reference

Europe PubMed Central

8 December 2017

Sawa A

2

1 reference

Europe PubMed Central

8 December 2017

Chen RW

3

1 reference

Europe PubMed Central

8 December 2017

Leeds P

4

1 reference

Europe PubMed Central

8 December 2017

Chuang DM

5

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Europe PubMed Central

8 December 2017

publication date

1 January 2004

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Europe PubMed Central

8 December 2017

The Pharmacogenomics Journal

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Europe PubMed Central

8 December 2017

4

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Europe PubMed Central

8 December 2017

5

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Europe PubMed Central

8 December 2017

336-344

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Europe PubMed Central

8 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.tpj.6500269

0 references

Mechanisms of action of valproate: a commentatory

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

21 January 2018

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

21 January 2018

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

21 January 2018

The human histone deacetylase family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

21 January 2018

Apicidin, a histone deacetylase inhibitor, induces apoptosis and Fas/Fas ligand expression in human acute promyelocytic leukemia cells

1 reference

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21 January 2018

Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway

1 reference

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21 January 2018

Life extension in Drosophila by feeding a drug.

1 reference

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21 January 2018

Neuroprotective properties of valproate: potential benefit for AD and tauopathies

1 reference

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21 January 2018

Increased expression of endoplasmic reticulum stress proteins following chronic valproate treatment of rat C6 glioma cells.

1 reference

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21 January 2018

Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons

1 reference

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21 January 2018

Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation

1 reference

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21 January 2018

Glyceraldehyde-3-phosphate dehydrogenase antisense oligodeoxynucleotides protect against cytosine arabinonucleoside-induced apoptosis in cultured cerebellar neurons

1 reference

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21 January 2018

Glyceraldehyde-3-phosphate dehydrogenase: nuclear translocation participates in neuronal and nonneuronal cell death

1 reference

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21 January 2018

Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx

1 reference

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21 January 2018

Domoic acid neurotoxicity in cultured cerebellar granule neurons is controlled preferentially by the NMDA receptor Ca(2+) influx pathway

1 reference

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21 January 2018

Kainate-induced excitotoxicity is dependent upon extracellular potassium concentrations that regulate the activity of AMPA/KA type glutamate receptors

1 reference

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21 January 2018

Electrophysiological evidence for glial-subtype glutamate transporter functional expression in rat cerebellar granule neurons.

1 reference

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21 January 2018

Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase isoforms during neuronal apoptosis.

1 reference

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21 January 2018

A Novel CRM1-mediated Nuclear Export Signal Governs Nuclear Accumulation of Glyceraldehyde-3-phosphate Dehydrogenase following Genotoxic Stress

1 reference

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21 January 2018

S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

21 January 2018

Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

21 January 2018

Overexpression and nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase in a transgenic mouse model of Huntington’s disease

1 reference

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21 January 2018

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

21 January 2018

Association of class II histone deacetylases with heterochromatin protein 1: potential role for histone methylation in control of muscle differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

21 January 2018

An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability

1 reference

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21 January 2018

Valproate administration to mice increases histone acetylation and 5-lipoxygenase content in the hippocampus

1 reference

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21 January 2018

The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

21 January 2018

Regulation of ER stress proteins by valproate: therapeutic implications.

1 reference

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21 January 2018

Valproic acid, a mood stabilizer and anticonvulsant, protects rat cerebral cortical neurons from spontaneous cell death: a role of histone deacetylase inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

21 January 2018

Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

21 January 2018

Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

21 January 2018

Involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and p53 in neuronal apoptosis: evidence that GAPDH is upregulated by p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

7 January 2021

based on heuristic

inferred from DOI database lookup

Subcellular distribution of glyceraldehyde-3-phosphate dehydrogenase in cerebellar granule cells undergoing cytosine arabinoside-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of glutamate uptake induces progressive accumulation of extracellular glutamate and neuronal damage in rat cortical cultures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

7 January 2021

based on heuristic

inferred from DOI database lookup

Glutamate transporters in glial plasma membranes: highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel protein complex distinct from mismatch repair binds thioguanylated DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500269

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.TPJ.6500269

1 reference

Europe PubMed Central

8 December 2017

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1 reference

Europe PubMed Central

8 December 2017

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