(Q45022698)

8 December 2017

title

Interactions of 5-deazapteridine derivatives with Mycobacterium tuberculosis and with human dihydrofolate reductases (English)

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Mycobacterium tuberculosis

8 December 2017

main subject

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author name string

Elaine F F da Cunha

1

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8 December 2017

Teodorico de Castro Ramalho

2

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8 December 2017

Ricardo Bicca de Alencastro

3

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8 December 2017

Elaine Rose Maia

4

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8 December 2017

publication date

1 October 2004

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Journal of Biomolecular Structure and Dynamics

8 December 2017

published in

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8 December 2017

volume

22

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8 December 2017

issue

2

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8 December 2017

page(s)

119-130

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Molecular mechanisms of drug resistance in Mycobacterium tuberculosis

8 December 2017

cites work

1 reference

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The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol

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In vitro activities of PS-15, a new dihydrofolate reductase inhibitor, and its cyclic metabolite against Mycobacterium avium complex

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Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs

21 January 2018

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Susceptibilities of Mycobacterium tuberculosis and Mycobacterium avium complex to lipophilic deazapteridine derivatives, inhibitors of dihydrofolate reductase

21 January 2018

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21 January 2018

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MD simulations of anthrax edema factor: calmodulin complexes with mutations in the edema factor "switch a" region and docking of 3'-deoxy ATP into the adenylyl cyclase active site of wild-type and mutant edema factor variants

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21 January 2018

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Comparison of two independent crystal structures of human dihydrofolate reductase ternary complexes reduced with nicotinamide adenine dinucleotide phosphate and the very tight-binding inhibitor PT523

21 January 2018

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21 January 2018

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21 January 2018

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Use of buildup and energy-minimization procedures to compute low-energy structures of the backbone of enkephalin.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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A density functional study on the complexation of ethambutol with divalent cations

21 January 2018

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Dihydrofolate reductase: multiple conformations and alternative modes of substrate binding

21 January 2018

1 reference

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10.1080/07391102.2004.10506988

21 January 2018

Identifiers

DOI

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8 December 2017

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