(Q45030481)

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A neuronal isoform of protein kinase G couples mitogen-activated protein kinase nuclear import to axotomy-induced long-term hyperexcitability in Aplysia sensory neurons.

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Europe PubMed Central

8 December 2017

A neuronal isoform of protein kinase G couples mitogen-activated protein kinase nuclear import to axotomy-induced long-term hyperexcitability in Aplysia sensory neurons (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729646&resulttype=core&format=json

12 May 2020

Edgar T Walters

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729646&resulttype=core&format=json

12 May 2020

author name string

Ying-Ju Sung

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729646&resulttype=core&format=json

12 May 2020

Richard T Ambron

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729646&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

1 August 2004

1 reference

Europe PubMed Central

8 December 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729646&resulttype=core&format=json

12 May 2020

24

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729646&resulttype=core&format=json

12 May 2020

7583-7595

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729646&resulttype=core&format=json

12 May 2020

34

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729646&resulttype=core&format=json

12 May 2020

Mechanisms for generating the autonomous cAMP-dependent protein kinase required for long-term facilitation in Aplysia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic GMP pathway is critical for inducing long-term sensitization of nociceptive sensory neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation causes a long-term hyperexcitability in the nociceptive sensory neurons of Aplysia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of partially phosphorylated forms of ERK by monoclonal antibodies reveals spatial regulation of ERK activity by phosphatases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ectopic mechanosensitivity in injured sensory axons arises from the site of spontaneous electrogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parallel molecular pathways mediate expression of distinct forms of intermediate-term facilitation at tail sensory-motor synapses in Aplysia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RNAs that interact with the fragile X syndrome RNA binding protein FMRP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct interactions between immunocytes and neurons after axotomy in Aplysia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axotomy- and autotomy-induced changes in the excitability of rat dorsal root ganglion neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal plasticity and signal transduction in nociceptive neurons: implications for the initiation and maintenance of pathological pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RISK-1: a novel MAPK homologue in axoplasm that is activated and retrogradely transported after nerve injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine-phosphorylated extracellular signal--regulated kinase associates with the Golgi complex during G2/M phase of the cell cycle: evidence for regulation of Golgi structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathobiology of neuropathic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The activity of the extracellular signal-regulated kinase 2 is regulated by differential phosphorylation in the activation loop

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term alteration of S-type potassium current and passive membrane properties in aplysia sensory neurons following axotomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic neuropathic pain is accompanied by global changes in gene expression and shares pathobiology with neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the mitogen activated protein kinase extracellular signal-regulated kinase 1 and 2 by the nitric oxide-cGMP-cGMP-dependent protein kinase axis regulates the expression of matrix metalloproteinase 13 in vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term potentiation in hippocampus involves sequential activation of soluble guanylate cyclase, cGMP-dependent protein kinase, and cGMP-degrading phosphodiesterase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity-dependent presynaptic facilitation and hebbian LTP are both required and interact during classical conditioning in Aplysia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fragile X mental retardation protein FMRP binds elongation factor 1A mRNA and negatively regulates its translation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling through NO and cGMP‐dependent protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marked increase in nitric oxide synthase mRNA in rat dorsal root ganglia after peripheral axotomy: in situ hybridization and functional studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cAMP modulates multiple K+ currents, increasing spike duration and excitability in Aplysia sensory neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of PKA and PKC in facilitation of evoked and spontaneous transmitter release at depressed and nondepressed synapses in Aplysia sensory neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A signal sequence mediates the retrograde transport of proteins from the axon periphery to the cell body and then into the nucleus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid electrical and delayed molecular signals regulate the serum response element after nerve injury: convergence of injury and learning signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downregulation of voltage-gated potassium channel alpha gene expression by axotomy and neurotrophins in rat dorsal root ganglia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axoplasmic importins enable retrograde injury signaling in lesioned nerve.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Painful neuropathy: altered central processing maintained dynamically by peripheral input

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatotopic organization and functional properties of mechanosensory neurons expressing sensorin-A mRNA in Aplysia californica.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathways that elicit long-term changes in gene expression in nociceptive neurons following nerve injury: contributions to neuropathic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Similar neuronal alterations induced by axonal injury and learning in Aplysia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic nucleotide-dependent protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a peptide specific for Aplysia sensory neurons by PCR-based differential screening.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identified target motor neuron regulates neurite outgrowth and synapse formation of aplysia sensory neurons in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term expansion and sensitization of mechanosensory receptive fields in Aplysia support an activity-dependent model of whole-cell sensory plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular injection of cAMP induces a long-term reduction of neuronal K+ currents

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term facilitation in Aplysia involves increase in transmitter release.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation by guanosine 3‘:5‘-monophosphate-dependent protein kinase of synthetic peptide analogs of a site phosphorylated in histone H2B

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanoafferent neurons innervating tail of Aplysia. I. Response properties and synaptic connections

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanoafferent neurons innervating tail of Aplysia. II. Modulation by sensitizing stimulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensory afferent impulses originate from dorsal root ganglia as well as from the periphery in normal and nerve injured rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolated identified Aplysia neurons in cell culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retrograde axonal transport of signal transduction proteins in rat sciatic nerve

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axoplasm enriched in a protein mobilized by nerve injury induces memory-like alterations in Aplysia neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression, purification, and characterization of the cGMP-dependent protein kinases I beta and II using the baculovirus system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integration of MAP kinase signal transduction pathways at the serum response element

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-lasting increase of nitric oxide synthase immunoreactivity, NADPH-diaphorase reaction and c-JUN co-expression in rat dorsal root ganglion neurons following sciatic nerve transection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous axoplasmic proteins and proteins containing nuclear localization signal sequences use the retrograde axonal transport/nuclear import pathway in Aplysia neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide synthase-like immunoreactivity in lumbar dorsal root ganglia and spinal cord of rat and monkey and effect of peripheral axotomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of peri-axonal inflammation in the development of thermal hyperalgesia and guarding behavior in a rat model of neuropathic pain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Injury-related behavior and neuronal plasticity: an evolutionary perspective on sensitization, hyperalgesia, and analgesia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retrograde transport of plasticity signals in Aplysia sensory neurons following axonal injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction from the cell surface to the nucleus through the phosphorylation of transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is reexpressed following axotomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and function of cyclic nucleotide-dependent protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel actin cDNA is expressed in the neurons of Aplysia californica

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aplysia CREB2 represses long-term facilitation: relief of repression converts transient facilitation into long-term functional and structural change

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presynaptic facilitation revisited: state and time dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide synthase activity in the molluscan CNS

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous action potential activity in isolated dorsal root ganglion neurons from rats with a painful neuropathy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Priming events and retrograde injury signals. A new perspective on the cellular and molecular biology of nerve regeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrinsic injury signals enhance growth, survival, and excitability of Aplysia neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dominant negative effects of H-Ras harboring a Gly to Ala mutation at position 60.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MAP kinase translocates into the nucleus of the presynaptic cell and is required for long-term facilitation in Aplysia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A nuclear localization signal targets proteins to the retrograde transport system, thereby evading uptake into organelles in aplysia axons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of gene expression by cyclic GMP-dependent protein kinase requires nuclear translocation of the kinase: identification of a nuclear localization signal

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axotomy increases the excitability of dorsal root ganglion cells with unmyelinated axons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term effects of axotomy on excitability and growth of isolated Aplysia sensory neurons in cell culture: potential role of cAMP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequestration of cAMP response element-binding proteins by transcription factor decoys causes collateral elaboration of regenerating Aplysia motor neuron axons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis and regulation of vasodilator-stimulated phosphoprotein serine 239 phosphorylation in vitro and in intact cells using a phosphospecific monoclonal antibody.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell type-specific changes of the membrane properties of peripherally-axotomized dorsal root ganglion neurons in a rat model of neuropathic pain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin induces temporally and mechanistically distinct phases of persistent PKA activity in Aplysia sensory neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation-dependent inhibition of protein phosphatase-1 by G-substrate. A Purkinje cell substrate of the cyclic GMP-dependent protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune-mediated alterations in nociceptive sensory function in Aplysia californica

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of protein kinase A contributes to the expression but not the induction of long-term hyperexcitability caused by axotomy of Aplysia sensory neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The induction of pain: an integrative review.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15329406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.1445-04.2004

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729646&resulttype=core&format=json

12 May 2020

release_adbg3344tfc7jh7qhrnvnxj47q

1 reference

https://api.fatcat.wiki/v0/release/adbg3344tfc7jh7qhrnvnxj47q

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729646&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729646&resulttype=core&format=json

12 May 2020

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