(Q45046030)

8 December 2017

title

Biomarker discovery: identification of a growth factor gene signature (English)

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8 December 2017

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A Loboda

1

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8 December 2017

M Nebozhyn

2

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8 December 2017

C Cheng

3

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8 December 2017

R Vessey

4

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8 December 2017

P Huang

5

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8 December 2017

H Dai

6

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8 December 2017

J W Watters

7

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8 December 2017

language of work or name

English

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publication date

22 April 2009

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Clinical Pharmacology & Therapeutics

8 December 2017

published in

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8 December 2017

volume

86

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8 December 2017

issue

1

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8 December 2017

page(s)

92-96

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Developing gene expression signatures of pathway deregulation in tumors

8 December 2017

cites work

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

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Oncogenic pathway signatures in human cancers as a guide to targeted therapies

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

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Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

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Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

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Drug target validation and identification of secondary drug target effects using DNA microarrays

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7 January 2021

Neuregulins: functions, forms, and signaling strategies

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7 January 2021

Akt stimulates aerobic glycolysis in cancer cells

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

7 January 2021

The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

7 January 2021

Akt-dependent transformation: there is more to growth than just surviving

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

7 January 2021

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

7 January 2021

Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

7 January 2021

Control of cell proliferation and growth by Myc proteins.

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

7 January 2021

A cell proliferation signature is a marker of extremely poor outcome in a subpopulation of breast cancer patients

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

7 January 2021

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

7 January 2021

A gene-expression signature as a predictor of survival in breast cancer

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

7 January 2021

Gene expression profiling predicts clinical outcome of breast cancer

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

7 January 2021

Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity.

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

7 January 2021

PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

7 January 2021

Molecular subtypes of breast cancer in relation to paclitaxel response and outcomes in women with metastatic disease: results from CALGB 9342

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https://api.crossref.org/works/10.1038%2FCLPT.2009.48

7 January 2021

Identifiers

DOI

10.1038/CLPT.2009.48

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8 December 2017

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