(Q45053077)

English

Quercetin, a flavonoid phytoestrogen, ameliorates experimental allergic encephalomyelitis by blocking IL-12 signaling through JAK-STAT pathway in T lymphocyte

scientific article published in September 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Quercetin, a flavonoid phytoestrogen, ameliorates experimental allergic encephalomyelitis by blocking IL-12 signaling through JAK-STAT pathway in T lymphocyte (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

author name string

Gladson Muthian

1

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

John J Bright

2

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

publication date

1 September 2004

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Journal of Clinical Immunology

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

24

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

542-552

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

https://scigraph.springernature.com/pub.10.1023/b:joci.0000040925.55682.a5

0 references

Estrogenic and antiestrogenic activities of flavonoid phytochemicals through estrogen receptor binding-dependent and -independent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How many people in the world have multiple sclerosis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex difference in Lewis rats in the incidence of recurrent experimental allergic encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor)

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Do soy isoflavones lower cholesterol, inhibit atherosclerosis, and play a role in cancer prevention?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

17 beta-estradiol inhibits cytokine, chemokine, and chemokine receptor mRNA expression in the central nervous system of female mice with experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A gender gap in autoimmunity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of dietary flavonoids in protection against cancer and coronary heart disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavonoids inhibit myelin phagocytosis by macrophages; a structure-activity relationship study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative bioavailability of the antioxidant flavonoid quercetin from various foods in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral contraceptives, rheumatoid arthritis, and androgens

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12 enhances IL-2 function by inducing CD25 expression through a p38 mitogen-activated protein kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The flavonoid Kaempferol suppresses the graft-versus-host reaction by inhibiting type 1 cytokine production and CD8+ T cell engraftment

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immunology of multiple sclerosis and its animal model, experimental allergic encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plants with traditional uses and activities, relevant to the management of Alzheimer's disease and other cognitive disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavonoids differentially regulate IFN gamma-induced ICAM-1 expression in human keratinocytes: molecular mechanisms of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Second signal activity of IL-12 on the proliferation and IL-2R expression of T helper cell-1 clone

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steroid hormone receptors and dietary ligands: a selected review.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavonoids exert diverse inhibitory effects on the activation of NF-kappaB.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of estrogen receptor-dependent transcription in a cell-free system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of experimental allergic encephalomyelitis via inhibition of IL-12 signaling and IL-12-mediated Th1 differentiation: an effect of the novel anti-inflammatory drug lisofylline

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen induces a potent suppression of experimental autoimmune encephalomyelitis and collagen-induced arthritis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of interleukin 12 p40 expression through an NF-kappa B half-site

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-gamma-deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-beta inhibits IL-12-induced activation of Jak-STAT pathway in T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of CD40 signaling pathway by tyrphostin A1 reduces secretion of IL-12 in macrophage, Th1 cell development and experimental allergic encephalomyelitis in SJL/J mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogenic actions in the brain: estrogen, phytoestrogens, and rapid intracellular signaling mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrphostin B42 inhibits IL-12-induced tyrosine phosphorylation and activation of Janus kinase-2 and prevents experimental allergic encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal models for autoimmune demyelinating disorders of the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple sclerosis: deeper understanding of its pathogenesis reveals new targets for therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beneficial role of dietary phytoestrogens in obesity and diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drugs in development for the treatment of multiple sclerosis: antigen non-specific therapies--an update

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral contraceptives and the incidence of multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple sclerosis and gender

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-inflammatory properties of plant flavonoids. Effects of rutin, quercetin and hesperidin on adjuvant arthritis in rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IkappaB kinases alpha and beta show a random sequential kinetic mechanism and are inhibited by staurosporine and quercetin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of NF-kappaB activation induced by bacterial lipopolysaccharide through Toll-like receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunomodulatory drugs for multiple sclerosis: a systematic review of clinical and cost effectiveness

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of flavonol derivatives on the carrageenin-induced paw edema in the rat and inhibition of cyclooxygenase-1 and 5-lipoxygenase in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E(2) production

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phytoestrogens in health and disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitexicarpin, a flavonoid from the fruits of Vitex rotundifolia, inhibits mouse lymphocyte proliferation and growth of cell lines in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse microglial cell lines differing in constitutive and interferon-gamma-inducible antigen-presenting activities for naive and memory CD4+ and CD8+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between sex hormones and magnetic resonance imaging lesions in multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoimmune rheumatic diseases in women

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of IL-12 in CNS and lymphoid organs of mice with experimental allergic encephalitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential influence of interleukin-12 in the pathogenesis of autoimmune and virus-induced central nervous system demyelination.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of soy phytoestrogens in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-12 regulates the proliferation of Th1, but not Th2 or Th0, clones.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for sex steroids in autoimmune diseases: a working hypothesis and supporting data.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12 augments antigen-dependent proliferation of activated T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-beta inhibits IL-2-induced tyrosine phosphorylation and activation of Jak-1 and Stat 5 in T lymphocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogenic activity of flavonoids in mice. The importance of estrogen receptor distribution, metabolism and bioavailability

1 reference

https://pubmed.ncbi.nlm.nih.gov/15359113

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/B:JOCI.0000040925.55682.A5

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 December 2017

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